BioWorld Science

May 17, 2022

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Hyaluronidase-expressing oncolytic virus VCN-11 shows promise as cancer immunotherapeutic

STK-002 confers a dose-dependent increase in OPA1 expression in ADOA retina

Lhotse Bio discovers lysophosphatidic acid receptor 1 antagonists

New STING agonists identified at Tyligand Bioscience

New RET inhibitors synthesized at Shanghai LiteDD

Suzhou Zelgen Biosciences patents G12C mutant GTPase KRAS inhibitors

New non-receptor tyrosine-protein kinase TYK2 inhibitors described by PharmaBlock Sciences

Multiple aging hallmarks show up as epigenetic changes

Novel zebrafish model of Opa1-mutated dominant optic atrophy

Intrathalamic administration of AVB.PGRN rescues pathology in Grn-null FTD mice

AstraZeneca selects IPF target under drug discovery collaboration with BenevolentAI

EDIT-202 iPSC-derived NK cell therapy shows tumor killing in vivo

Osivax collaborates with NIAID to combine OVX-836 with NIAID influenza vaccine candidates

Sosei Heptares and Kallyope collaborate to identify gastrointestinal GPCR targets

Sosei and Kallyope have entered a strategic research collaboration to identify and validate novel G protein-coupled receptor (GPCR) targets with a goal of creating new drug discovery programs in the area of gastrointestinal diseases. Read More

Nanocapsules efficiently deliver single CRISPR-Cas9 across the blood-brain barrier

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Hematopoietic stem cell research points to leukemia’s early roots

BioWorld Science

Hematopoietic stem cell (HSC) research over the past century has shown that leukemia may be driven by an invisible hand of inflammation. The bone marrow and...

Illustration of a nerve cell with DNA double helix

Molecular signatures show subtypes in neurodegenerative diseases

BioWorld Science

Parkinson’s disease is a progressive neurodegenerative disorder best known for its motor symptoms. However, a proportion of patients also develop dementia as the...

More than two to tango: multispecifics at ESMO TAT

BioWorld Science

Multispecifics took center stage at this year’s ESMO TAT, emerging as one of the hottest trends in oncology research. Unlike traditional small-molecule drugs or...