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BioWorld - Friday, December 5, 2025

Small molecule

Home » Topics » Drugs » Small molecule
  • Australian coins and bills
    Dec. 5, 2025
    By Tamra Sami

    Kazia raises AU$50M to advance PI3K/mTOR inhibitor paxalisib

    Kazia Therapeutics Ltd. raised AU$50 million (US$33.15 million) in a private placement of equity securities to advance lead candidate paxalisib, a brain-penetrant dual PI3K/mTOR inhibitor in clinical trials for brain cancer and advanced breast cancer.
  • Male hair loss
    Dec. 3, 2025
    By Karen Carey

    Cosmo data positive for first new hair-loss approach in decades

    Shares of Cosmo Pharmaceuticals NV rose sharply on Dec. 3 following top-line pivotal phase III data showing a statistically significant and clinically meaningful improvement in male androgenetic alopecia patients receiving clascoterone 5%, the first topical androgen receptor inhibitor, which uses the same active ingredient as the company’s acne treatment, Winlevi.
  • Glass of water and tablets
    Dec. 3, 2025
    By Jennifer Boggs

    Pharvaris’ oral deucrictibant hits endpoints in acute HAE trial

    Pharvaris NV looks to start filing marketing applications in the first half of 2026 on the back of positive phase III data showing oral bradykinin B2 receptor antagonist deucrictibant hit all primary and secondary endpoints as an on-demand treatment for hereditary angioedema (HAE) attacks.
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