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BioWorld - Tuesday, December 9, 2025

Breakthrough therapy

Home » Topics » Regulatory » Breakthrough therapy
  • Antibodies attacking cancer cell
    Oct. 22, 2025
    By Marian (YoonJee) Chu

    Innovent rings up $11.4B deal with Takeda for three I-O/ADC assets

    Takeda Pharmaceutical Co. Ltd. agreed to codevelop and commercialize up to three of Innovent Biologics Co. Ltd.’s immuno-oncology (I-O) and antibody-drug conjugate (ADC) candidates with the signing of a $11.4 billion deal, including $1.2 billion paid up front.
  • Knee pain illustration
    June 10, 2025
    By Karen Carey

    Allay’s $57.5M extends postsurgical pain relief with ATX-101

    As it advances its nonopioid analgesic ATX-101 breakthrough therapy through a phase IIb registration trial, Allay Therapeutics secured $57.5 million in a series D round, which included an investment from the company’s Japanese partner.
  • Knee pain illustration
    June 6, 2025
    By Karen Carey

    Allay’s $57.5M extends postsurgical pain relief with ATX-101

    As it advances its nonopioid analgesic ATX-101 breakthrough therapy through a phase IIb registration trial, Allay Therapeutics secured $57.5 million in a series D round, which included an investment from the company’s Japanese partner. ATX-101, a configuration of sodium ion channel blocker bupivacaine and a biopolymer, which is in a phase IIb registration study, is designed to offer pain relief following total knee arthroplasty.
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