PHILADELPHIA – Against a backdrop of President Donald Trump's controversial comments about U.S.-Britain trade Wednesday, panelists at the Biotechnology Innovation Organization's (BIO) international convention painted a mixed picture of Brexit's potential impacts. Preparations for likely disruptions started at day one following the referendum, an EMA representative said. Despite that, "if there's one thing certain about Brexit, it's that's there's lots of uncertainties," said Tineke Van hooland, chairwoman of Bio.be, a trade organization representing Belgian biotechs.