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BioWorld - Wednesday, June 17, 2026
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Home » Epizyme updates phase II data for tazemetostat
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Epizyme updates phase II data for tazemetostat

June 15, 2017
By Michael Fitzhugh
Interim data from Epizyme Inc.’s ongoing phase II trial of EZH2 inhibitor tazemetostat boosted company shares (NASDAQ:EPZM) Wednesday as investors embraced news that 92 percent of patients with relapsed or refractory follicular lymphoma and EZH2-activating mutations treated with the experimental therapy saw their tumors shrink. People with the same mutation and diffuse large B-cell lymphoma (DLBCL) also benefited, though at a lower rate than seen in an earlier preview of the data. Both cancers are forms of non-Hodgkin lymphoma.
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