SAN DIEGO – One of the central topics of the BIO 2017 International Convention is "breakthroughs." For four days, San Diego will be at the epicenter of discussions about the exciting future that biotechnology will create in terms of new medicines and products and services that will make our lives better. From a scientific point of view, we appear to be on the verge of a number of tipping points in our understanding of disease biology and pathways that will lead to new creative medicines.