CHICAGO – The initial excitement and big buzz about Natural Orifice Translumenal Endoscopic Surgery®(NOTES) has been replaced with the heavy lifting of entering hard, long clinical trials that carefully evaluate the potential benefits and risks associated with the novel technique. The 5th meeting of the Natural Orifice Surgery Consortium for Assessment and Research® (NOSCAR) was held here with exciting news of initial human trials being performed. (Medical Device Daily)