I. COMMENCED TRADING IN AUGUST
Company (Symbol)# Date Filed Date Comm. Shares/Units (M) Price Shares Out (M)@ Lead, Other Underwriters Gross (US$M) Post-Offering Market Cap (M)%
INITIAL OFFERINGS
Sucampo Pharmaceuticals Inc. (SCMP)1 6/19/06 8/3/07 3.125S $11.50 41.7 Cowen & Co. CIBC World Markets Leerink Swann & Co. $35.94 $479.55
Total: $35.94M

Number of IPOs in August: 1

Average value of August IPOs: $35.94

Number of IPOs in 2007: 31

Total raised in IPOs in 2007: $1,563.20M

Average value of IPOs in 2007: $50.43M
FOLLOW-ON OFFERINGS
Company (Symbol)# Date Filed Date Comm. Shares/ Units (M) Price Shares Out (M)@ Lead, Other Underwriters Gross (M) Post-Offering Market Cap (M)%
NeoStem Inc.(AMEX:NBS)2 8/14 8/14 1.27U $4.96 4 Mercer Capital Ltd. $6.3 $19.84
Total: $6.3M

Number of follow-on offerings in August: 1

Average value of August follow-ons: $6.3M

Number of follow-on offerings in 2007: 39

Total raised in follow-ons in 2007: $2,480.70M

Average value of follow-ons in 2007: $63.61M

Notes:
# Unless otherwise indicated, shares are traded on the Nasdaq exchange.@ This column reflects the shares outstanding following the offering, when disclosed. % Market capitalization is calculated based on the offering price. Currency conversions are based on exchange rates at the time of the deal. AMEX = American Stock Exchange.

1 Sucampo's IPO was worth $43.1M, with a stockholder offering 625,000 shares in addition to the 3.125M offered by the company. Underwriters exercised in full their option for 562,500-shares, which were sold by the stockholder.

2 NeoStem sold 1.27M units, each consisting of one share of common stock and half of a five-year warrant to purchase another share at $6.

II. FILED AND PENDING
Company (Symbol/Proposed Symbol)#* Date Filed Shares/ Units (M) Price Range Shares Out (M)@ Lead, Other Underwriters Value (M)
INITIAL OFFERINGS
Adnexus Therapeutics Inc. (ADNX) 8/22/07 N/A N/A N/A Lehman Brothers UBS Securities (co-lead),Cowen & Co. Lazard Freres & Co. LLC $86
Anacor Pharmaceuticals Inc. (ANAC) 8/31/07 N/A N/A N/A Morgan Stanley & Co. Inc. Cowen & Co. LLC (co-lead) Pacific Growth Equities LLC Needham & Co. LLC $57.5
Archemix Corp. (ARCH) 7/25/07 N/A N/A N/A Banc of America Securities Bear, Stearns & Co. Inc.Cowen and Co. $69
ARYx Therapeutics Inc. (ARYX) 8/31/07 N/A N/A N/A Morgan Stanley & Co. Inc. CIBC World Markets Corp. Jefferies & Co. Inc. Leerink Swann & Co. Inc. $86.25
Bioheart Inc. (BHRT) 2/13/07 N/A N/A 21.5 BMO Capital Markets Corp. Janney Montgomery Scott (co-lead) Merriman Curhan Ford & Co. $35
Biolex Inc. (BLEX) 8/14/07 N/A N/A N/A Lehman Brothers Inc. Deutsche Bank Securities (co-lead) Leerink Swann & Co. Inc. $70
Genoptix Inc. (GXDX) 8/1/07 N/A N/A N/A Lehman Brothers Banc of America Sec. Cowen and Co. $86.25
Insys Therapeutics Inc. (INRX) 8/20/07 N/A N/A N/A Banc of America Securities UBS Investment Bank (co-lead) JMP Securities Natixis Bleichroeder $86.25
Light Sciences Oncology Inc. (LSON) 4/21/06 5.25S $14-$16 18.5 Cowen & Co. Wachovia Securities (co-lead) Jefferies & Co. Thomas Weisel Partners $78.75
MAP Pharmaceuticals Inc. (MAPP) 6/18/07 N/A N/A N/A Merrill Lynch & Co. Morgan Stanley (co-lead) Deutsche Bank Sec. $86.25
Merrion Pharmaceuticals Ltd. (MERR)1 4/3/07 N/A N/A N/A Punk, Ziegel & Co. Goodbody Stockbrokers Stanford Group Co. $46
MonoSol Rx Inc.

(MSRX)

 5/14/07 4S $16-$18 N/A Cowen and Co. CIBC World Markets Susquehanna Financial $68
Nanoshere Inc. (NSPH) 8/13/07 N/A N/A N/A Credit Suisse Piper Jaffray Leerink Swann & Co. Allen & Co. LLC $100
NovaBay Pharmaceuticals

Inc (AMEX:NBY;TSX:NBY)2

 2/15/07 5S $4-$6 21.1 Dundee Securities Desjardins Sec. International Blackmont Capital $25
Peplin Inc.

(PLIN)3

 8/10/07 N/A N/A N/A Merrill Lynch & Co.

Cowen & Co. LLC

Thomas Weisel Partners

Leerink Swann & Co.

Merrill Lynch International Wilson HTM		 $75
Precision Therapeutics Inc. 8/24/07 N/A N/A N/A JP Morgan Piper Jaffray (co-lead) JMP Securities $80.5
Reliant Pharmaceuticals Inc. (NYSE:RRX) 8/10/07 N/A N/A N/A Goldman, Sachs & Co. Merrill Lynch & Co. (co-lead) Bank of America Securities Lazard Capital Markets $400
Talecris Biotherapeutics Holdings Corp. (TLCR) 7/30/07 N/A N/A N/A Morgan Stanley Goldman Sachs & Co. J.P. Morgan $1B
Targanta

Therapeutics

Corp. (TARG)		 5/14/07 N/A N/A N/A Credit Suisse Securities

Cowen and Co.

Lazard Capital Markets Leerink Swann and Co.		 $86.25
FOLLOW-ON OFFERINGS
Bioxel Pharma

Inc. (Canada; CDNX:BIP)4

 7/9/07 N/A N/A N/A Paradigm Capital

Laurentian Bank Sec.

 N/A
Chemokine Therapeutics Corp. (Canada; TSX:CTI; OTC BB: CHKT) 5/30/07 N/A N/A N/A GMP Securities $25
Neurobiological Technologies Inc. (NTII) 8/13/07 N/A N/A N/A Merriman Curhan Ford $75
Neurochem Inc. (NRMX) 1/18/07 N/A N/A N/A N/A $102
Notes:
# Unless otherwise indicated, shares are traded on the Nasdaq exchange; general shelf registration statements are not included until action is taken on the filing.

* Stock symbols for companies seeking to complete IPOs are proposed.

@ This column reflects the shares outstanding following the offering, when disclosed.

The value of all offerings is based on either the midpoint of the price range listed in the company's SEC filing or the most recent closing stock price before the offering was announced. In some cases, the company has not disclosed the number of shares to be offered or a price range. Then, the value is the maximum aggregate offering price listed in the SEC filing.

\N/A = Not available, applicable or reported.

AMEX = American Stock Exchange; CDNX = Canadian Venture Exchange; NYSE = New York Stock Exchange; OTC BB = Over-the-Counter Bulletin Board; TSX = Toronto Stock Exchange.

1 Merrion plans to list American depositary shares on Nasdaq and ordinary shares in a secondary listing on the Irish Enterprise Exchange, both under the ticker "MERR."

2 NovaBay is seeking a dual listing on the American and Toronto stock exchanges.

3 Peplin Ltd., of Australia, established the U.S. subsidiary to facilitate an IPO.

4 Bioxel filed for a Canadian offering of units consisting of one common share and one-half of a common share purchase warrant.