I. COMMENCED TRADING IN DECEMBER

Company (Symbol)
#
Date Filed Date Comm. Shares/Units (M) Price Shares Out (M)
@
Lead, Other Underwriters Gross (US$M) Post-Offering Market Cap (M)
%
INITIAL OFFERINGS
Hybrigenics SA (France; PARIS: ALHYG)
1
ND 12/26** 0.708S and W €8.70 10.1 N/A €6.16 ($23.8) E87.9 ($130)
NovaBayPharmaceuticals
Inc. (AMEX:NBY)
2/14 10/26* 5S $4 21.1 Dundee Securities Inc.
Desjardins Sec. (co-lead)
Blackmont Capital
Dawson James Sec.
$20 $84.4
* NovaBay's IPO was completed in October but not listed in that month's chart.

Total: $43.8M
Number of IPOs in December: 2Average value of December IPOs: $21.9
Number of IPOs in 2007: 41Total raised in IPOs in 2007: $1,858.36M
Average value of IPOs in 2007: $45.33M
FOLLOW-ON OFFERINGS
Company (Symbol)
#
Date Filed Date Comm. Shares/Units (M) Price Shares Out (M)
@
Lead, Other Underwriters Gross (M) Post-Offering Market Cap (M)
%
Anesiva Inc. (ANSV)
2
12/13 12/26 12.3S $4.05 40.3 Pacific Growth Equities
Broadpoint Capital Inc.
Fortis Securities LLC
$49.8 $163.2
EpiCept Corp. (EPCT) 10/14 12/4 3.3S and W for 1.7S $1.50 46.8 Rodman & Renshaw $4.95 $70.2
Total: $54.75M
Number of follow-on offerings in December: 2 Average value of December follow-ons: $27.38M
Number of follow-on offerings in 2007: 51 Total raised in follow-ons in 2007: $2,910.24M
Average value of follow-ons in 2007: $57.06M
Notes:
# Unless otherwise indicated, shares are traded on the Nasdaq exchange.
@ This column reflects the shares outstanding following the offering, when disclosed.
% Market capitalization is calculated based on the offering price. Currency conversions are based on exchange rates at the time of the deal.
AMEX = American Stock Exchange
1 Hybrigenics went public on the Alternext market of the Euronext Paris stock exchange.
2 Includes Anesiva's overallotment option: 1.2M shares.
II. FILED AND PENDING
Company (Symbol/ Proposed Symbol)
#*
Date Filed Shares/Units (M) PriceRange Shares Out (M)
@
Lead, Other Underwriters Value (M)
INITIAL OFFERINGS
AegerionPharmaceuticals
Inc. (AEGR)
11/21/07 N/A N/A N/A Piper Jaffray
Thomas Weisel Partners (co-lead)
Lazard Capital Markets
Collins Stewart LLC
$86
Anacor Pharmaceuticals
Inc. (ANAC)
8/31/07 N/A N/A N/A Morgan Stanley & Co. Inc.
Cowen & Co. LLC (co-lead)
Pacific Growth Equities LLC
Needham & Co. LLC
$57.5
Archemix Corp.(ARCH) 7/25/07 N/A N/A N/A Banc of America Securities
Bear, Stearns & Co. Inc.
Cowen and Co.
$69
Bioheart Inc. (BHRT)
1
2/13/07 3.575S $14-$16 16.9 BMO Capital Markets Corp.
Janney Montgomery Scott (co-lead)
Merriman Curhan Ford & Co.
$53.6
Biolex Inc.(BLEX) 8/14/07 N/A N/A N/A Lehman Brothers Inc.
Deutsche Bank Securities (co-lead)
Leerink Swann & Co. Inc.
$70
ChemocentryxInc. (CCXI) 11/12/07 N/A N/A N/A Credit Suisse Securities LLC
Cowen and Co.
Leerink Swann
Lazard Capital Markets
$57.5
Elixir Pharmaceuticals Inc. (ELXR) 9/24/07 5S $14-$16 143.5 Credit Suisse Securities LLC
Pacific Growth Equities
Leerink Swann LLC
$75
Insys Therapeutics Inc. (INRX) 8/20/07 N/A N/A N/A Banc of America Securities
UBS Investment Bank (co-lead)
JMP Securities
Natixis Bleichroeder
$86.25
Light Sciences Oncology Inc.
(LSON)
4/21/06 5.25S $14-$16 18.5 Cowen & Co.
Wachovia Securities (co-lead)
Jefferies & Co.
Thomas Weisel Partners
$78.75
Merrion Pharmaceuticals Ltd. (MERR)
2
4/3/07 4S $6-$7 15 Punk, Ziegel & Co.
Goodbody Stockbrokers
Stanford Group Co.
$26
MonoSol Rx Inc.(MSRX) 5/14/07 4S $16-$18 N/A Cowen and Co.
CIBC World Markets
Susquehanna Financial
$68
Peplin Inc.(PLIN)
3
8/10/07 N/A N/A N/A Merrill Lynch & Co.
Cowen & Co. LLC
Thomas Weisel Partners
Leerink Swann & Co.
Merrill Lynch International
Wilson HTM
$75
Prometheus Laboratories Inc. 12/19/07 N/A N/A N/A Goldman Sachs & Co.
Credit Suisse (co-lead)
$100
RXi Pharmaceuticals Corp. (RXIP;unit of CytRx Corp.) 10/30/07 10.8S N/A N/A N/A N/A
Talecris Biotherapeutics Holdings Corp. (TLCR) 7/30/07 N/A N/A N/A Morgan Stanley
Goldman Sachs & Co.
J.P. Morgan
$1B
Xanodyne Pharmaceuticals Inc. (XANO) 11/9/07 N/A N/A N/A Morgan Stanley
Deutsche Bank (co-lead)
RBC Capital Markets
Natexis Bleichroeder
$86.25
XDx Inc. (XDXI) 10/24/07 N/A N/A N/A J.P. Morgan Securities Inc.
Morgan Stanley & Co. (co-lead)
Piper Jaffray & Co.
JMP Securities LLC
$86.3
FOLLOW-ON OFFERINGS
Bioxel Pharma Inc. (Canada; CDNX:BIP)
4
7/9/07 N/A N/A N/A Paradigm Capital
Laurentian Bank Sec.
N/A
Chemokine Therapeutics Corp. (Canada;TSX:CTI; OTC BB: CHKT) 5/30/07 N/A N/A N/A GMP Securities $25
WITHDRAWN AND POSTPONED
Akela Pharma Inc.
(Canada; TSX:AKL; AKLA) 5
10/12/07
12/20/07
5.3S $6-$8 17 Lazard Capital Markets
Oppenheimer & Co.
Broadpoint
$37.1
Precision Therapeutics Inc. (PRCN) 6 8/24/07
12/7/07
N/A N/A N/A JP Morgan
Piper Jaffray (co-lead)
JMP Securities
$80.5

Notes:
# Unless otherwise indicated, shares are traded on the Nasdaq exchange; general shelf registration statements are not included until action is taken on the filing.
* Stock symbols for companies seeking to complete IPOs are proposed.
@ This column reflects the shares outstanding following the offering, when disclosed. The value of all offerings is based on either the midpoint of the price range listed in the company's SEC filing or the most recent closing stock price before the offering was announced. In some cases, the company has not disclosed the number of shares to be offered or a price range. Then, the value is the maximum aggregate offering price listed in the SEC filing.
N/A = Not available, applicable or reported. CDNX = Canadian Venture Exchange; NYSE = New York Stock Exchange; OTC BB = Over-the-Counter Bulletin Board; TSX = Toronto Stock Exchange.
1 Bioheart's overallotment option: 536,250 shares.
2 Merrion plans to list American depositary shares on Nasdaq and ordinary shares in a secondary listing on the Irish Enterprise Exchange, both under the ticker "MERR."
3 Peplin Ltd., of Australia, established the U.S. subsidiary to facilitate an IPO.
4 Bioxel filed for a Canadian offering of units consisting of one common share and one-half of a common share purchase warrant.
5 Akela terminated plans for an IPO in the U.S. due to unfavorable market conditions for small and micro-cap companies.
6 Precision's IPO was set aside after announcing a planned merger with Oracle Healthcare Acquisition Corp.