Biotech Co.*
(Country;
Symbol)

Pharma Co.
(Country)

Product

Terms/Details (Date)


Acorda
Therapeutics
Inc.*

Cardinal Health

Two-year deal to expand the sales force for Acorda's Zanaflex Capsules

Cardinal will provide about 160 contract sales representatives to address the primary care market (11/10)

BioDelivery
Sciences
International
Inc.
(BDSI)

Aveva Drug Delivery Systems Inc.

Aveva will prepare supplies for Phase III trials and commercial manufacturing of BDSI's BEMA Fentanyl

The product is an oral adhesive disc formulation of the narcotic fentanyl; Aveva will exclusively manufacture and supply the discs (11/8)

Bioxel Pharma
Inc.
(Canada;
CDNX:BIP)

Undisclosed European manufacturer

Renewable two-year deal under which Bioxel will manufacture and supply paclitaxel

Paclitaxel deliveries to the generic manufacturer are expected to generate sales of $1.5M to $2M per year for Bioxel (10/27)

Cellegy
Pharmaceuticals
Inc.
(CLGY)

New Harbor Corp.

New Harbor got rights in China to a nitric oxide donor product for treating anal disorders

NHC will work through PUMC Pharmaceuticals Co. Ltd. to bring products to market in China; Cellegy would get royalties on sales (11/22)

Cubist
Pharmaceuticals
Inc.
(CBST)

ACS Dobfar SpA (Italy)

ACS was named the single- source supplier of the active ingredient for Cubist's antibiotic drug Cubicin

ACS has been supplying the ingredient for clinical trials since 1998; it now will be the only supplier (11/30)

GenTel
BioSurfaces
Inc.*

Abnova Corp. (Taiwan)

Deal to combine technologies to develop multiplex immunoassays

Terms of the deal were not disclosed (11/9)

Microbia Inc.*

Ranbaxy Laboratories Ltd. (India)

Deal to improve the bio-manufacturing process for a Ranbaxy product

Microbia is entitled to R&D funding and potential development milestone payments (11/1)

ProBioGen AG*
(Germany)

SAFC Biosciences (unit of Sigma-Aldrich Group)

Deal under which SAFC will market ProBioGen's cell line engineering services

The services cover development of high-titer cells for production of biotherapeutics; terms were not disclosed (11/1)

RxKinetix Inc.*

Indian Immunologicals Ltd. (India)

RxKinetix will work to develop improved formulations of a hepatitis B vaccine

The vaccine will be formulated in RxKinetix's ProJuvant delivery platform; terms of the deal were not disclosed (11/2)

SciGen Ltd.
(Singapore;
ASX:SIE)

Bioton (Poland) and Hefei Life Science & Technolology Investments and Development (China)

They established a joint venture to manufacture biopharmaceuticals in China

Among the drugs to be produced there will be SciGen's insulin and hepatitis B products; Hefei has a deal with SciGen to distribute SciGen products in China (12/13)

TolerRx Inc.*

Abbott Laboratories

Deal under which Abbott will manufacture TolerRx's TRX4 monoclonal antibody

Abbott will supply the product for clinical trials and potential commercial launch; terms were not disclosed (11/29)

Viragen Inc.
(AMEX:VRA)

Kuhnil Pharm Co. Ltd. (South Korea)

Kuhnil got rights to distribute Multiferon in South Korea

Viragen gets an up-front fee; Kuhnil gets exclusive rights for 10 years; further terms were not disclosed (12/6)

ViroPharma
Inc.
(VPHM)

Eli Lilly and Co.

Amended manufacturing deal calls for Lilly to increase its supply of Vancocin

ViroPharma, expecting a possible increase in demand for the Clostridium difficile infection product, will pay Lilly up to $4.5M more than provided for in the original contract through early 2006 (11/3)


Notes:

# The information in the chart does not cover agricultural agreements or those between biotech companies.

* Private companies are indicated with an asterisk.

Unless otherwise noted, stock symbols listed are on the Nasdaq market.

ASX = Australian Stock Exchange; AMEX = American Stock Exchange; CDNX = Canadian Venture Exchange.