Medicure Inc., of Winnipeg, Manitoba, said it received a U.S. patent covering several newly discovered therapeutics for treatment of cardiovascular diseases. No further information was disclosed.

Promega Corp., of Madison, Wis., said it received U.S. Patent No. 6,159,693 titled "Nucleic Acid Detection." It covers highly sensitive genotyping and single nucleotide polymorphism scoring technology.

ProtoGene Laboratories Inc., of Menlo Park, Calif., said it received U.S. Patent No. 6,177,558. It covers methods for ensuring effective delivery of very small volumes of reagents to surfaces for in situ synthesis of oligonucleotides.

Situs Corp., of San Diego, said it received U.S. Patent Nos. 6,139,535 and 6,171,298. They cover the company's UROS Infusor and its use.

Structural Bioinformatics Inc., of San Diego, said it received U.S. Patent No. 6,125,235. It covers technology for generating 3-D protein structures.