* Calgene Inc., of Davis, Calif., was issued U.S. patent No.5,545,817, which provides a method for enhancing expression of agene in a plastid by using a gene sequence preferred by the plantplastid; and U.S. patent No. 5,545,818, co-owned with RutgersUniversity, which covers expression of Bacillus thuringiensisinsecticidal protein in plant chloroplasts.

* Columbia Laboratories Inc., of Miami, was issued U.S. patent No.5,543,150 covering the technology used in its vaginally deliverednatural progesterone gel, Crinone, to allow the sustained and targetedvaginal delivery of progesterone to the uterus.

* Cytogen Inc., of Princeton, N.J., was issued U.S. patent No.5,538,866, titled "Prostate Specific Membrane Antigen," claimingthe nucleotide sequence encoding PSMA.

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