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BioWorld - Friday, January 16, 2026
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Home » Recent PI3K-delta troubles don’t deter confidence in drug class, says MEI Pharma CEO
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Recent PI3K-delta troubles don’t deter confidence in drug class, says MEI Pharma CEO

Feb. 1, 2022
By Jennifer Boggs
Last week, Incyte Corp. said it was pulling its NDA seeking accelerated approval for the PI3K-delta inhibitor parsaclisib in three non-Hodgkin lymphoma subtypes, a move that followed recent decisions by Gilead Sciences Inc. and Secura Bio Inc. to withdraw from U.S. commercialization their respective PI3K-delta inhibitors in indications for which they’d received accelerated approval. But the recent spate of headlines is hardly “a condemnation” on the entire class of drugs, said Dan Gold, CEO of MEI Pharma Inc., which is aiming for a potential accelerated approval filing of its own PI3K-delta drug, zandelisib, this year.
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