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» AZD-6422, a novel dnTGFββRII-armored, CLDN18.2-targeted CAR T therapeutic
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Immuno-oncology
AZD-6422, a novel dnTGFββRII-armored, CLDN18.2-targeted CAR T therapeutic
Nov. 16, 2023
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CLDN18 is a cell surface membrane protein involved in the formation of tight junctions, and the expression of its CLDN18.2 isoform has been observed in pancreatic, gastric and esophageal tumors.
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