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BioWorld - Wednesday, May 1, 2024
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» Arvinas Operations patents new Raf kinase B mutant degradation inducers
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Cancer
Arvinas Operations patents new Raf kinase B mutant degradation inducers
April 5, 2024
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Arvinas Operations Inc. has disclosed proteolysis targeting chimera (PROTAC) compounds consisting of a cereblon E3 ubiquitin ligase binding moiety coupled to a Raf kinase B G466V and/or V600E mutant targeting agent through a linker.
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