Children’s Hospital of Fudan University, Sydney Children’s Hospital and the University of Sydney have jointly patented new antibody-drug conjugates comprising an antibody targeting GD2 ganglioside covalently linked to cytotoxic drugs potentially useful for the treatment of osteosarcoma.

Beijing Double-Crane Runchuang Technology Co. Ltd. has discovered new Toll-like receptor 7 (TLR7) and/or TLR8 antagonists potentially useful for the treatment of rheumatoid arthritis, systemic lupus erythematosus, cutaneous lupus erythematosus, dermatomyositis, hidradenitis suppurativa, polymyositis, psoriasis and Sjogren’s syndrome, among others.

Inventisbio Co. Ltd. and Inventisbio LLC have disclosed new proteolysis targeting chimera (PROTAC) compounds comprising an E3 ubiquitin ligase-binding moiety coupled to a signal transducer and activator of transcription 6 (STAT6)-targeting moiety potentially useful for the treatment of cancer.