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Home » Topics » Regulatory » Patents

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US Fed Circuit rules in favor of Moderna in patent squabble

June 4, 2025
By Mari Serebrov
No Comments
Moderna Inc. once again emerged the winner in a court skirmish over claims that its COVID-19 vaccine infringed two Alnylam Pharmaceuticals Inc. patents. The U.S. Court of Appeals for the Federal Circuit issued a precedential opinion May 4, agreeing with a federal district court in Delaware that Moderna didn’t infringe the patents. For both courts, the decision was based on a single issue of claim construction.
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Cancer

Prelude Therapeutics describes new SMARCA2 and SMARCA4 degradation inducers

June 4, 2025
Prelude Therapeutics Inc. has described proteolysis targeting chimera (PROTAC) compounds comprising a cereblon (CRBN) E3 ubiquitin ligase binding moiety covalently linked to a probable global transcription activator SNF2L2 (SMARCA2; BAF190B; SNF2-α) or transcription activator BRG1 (SMARCA4; BAF190A; SNF2-β) targeting moiety through a linker. They are reported to be useful for the treatment of cancer.
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Cancer

STAT3 inhibitors disclosed in Altay Therapeutics patent

June 4, 2025
Altay Therapeutics Inc. has divulged signal transducer and activator of transcription 3 (STAT3) inhibitors reported to be useful for the treatment of cancer, autoimmune disease, diabetes, inflammatory disorders, muscular dystrophy, neurodegeneration and thyroid disorders.
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Neurology/psychiatric

Sensorium Therapeutics discovers new SERT inhibitors

June 4, 2025
Sensorium Therapeutics Inc. has identified mesembrine analogues acting as serotonin transporter (SERT) inhibitors reported to be useful for the treatment of neurological disorders.
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Nephrology

Shanghai Qilu Pharmaceutical divulges new CYP11B2 inhibitors

June 4, 2025
Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. has synthesized cytochrome P450 11B2, mitochondrial (CYP11B2; aldosterone synthase; ALDOS) inhibitors reported to be useful for the treatment of hypertension, diabetic nephropathy, chronic kidney disease and primary aldosteronism.
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Cancer

Transition Bio patents new YTHDC1 inhibitors for AML

June 4, 2025
Transition Bio Ltd. has disclosed YTH domain-containing protein 1 (YTHDC1; YT521-B) inhibitors reported to be useful for the treatment of acute myeloid leukemia (AML).
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Cancer

Nanjing Synnocare Pharmaceutical Technology discovers new PARG inhibitors

June 3, 2025
Nanjing Synnocare Pharmaceutical Technology Co. Ltd. has described poly(ADP-ribose) glycohydrolase (PARG) inhibitors reported to be useful for the treatment of cancer.
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Cancer

New SMARCA2 inhibitors disclosed in Galapagos patent

June 3, 2025
Galapagos NV has divulged probable global transcription activator SNF2L2 (SMARCA2; BAF190B; SNF2-α) inhibitors reported to be useful for the treatment of cancer.
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Neurology/psychiatric

Astellas Engineered Small Molecules describes new PARP inhibitors for neuronal injury

June 3, 2025
Astellas Engineered Small Molecules US Inc. has identified poly(ADP-ribose) polymerase (PARP) inhibitors, particularly PARP-1 (ARTD1), reported to be useful for the treatment of neuronal injury.
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Immune

Kangbaida Biotechnology divulges new TLR7 and TLR8 antagonists

June 3, 2025
Kangbaida (Sichuan) Biotechnology Co. Ltd. has synthesized pyrrolidine derivatives acting as Toll-like receptor 7 (TLR7) and/or (TLR8) antagonists reported to be useful for the treatment of autoimmune disease.
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