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BioWorld - Monday, March 2, 2026
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Home » Glutathione S-transferase inhibitor displays robust efficacy in lung cancer models
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Cancer

Glutathione S-transferase inhibitor displays robust efficacy in lung cancer models

Dec. 17, 2024

Glutathione S-transferase (GSTP) is an enzyme involved in the detoxification of several xenobiotics such as tobacco carcinogens or cisplatin drugs and is overexpressed in KRAS-mutant lung, colon and pancreatic cancer, among others. The upregulation of GSTP may partially contribute to chemotherapy and radiotherapy resistance.

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