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BioWorld - Wednesday, January 14, 2026
Home » UK Biobank

Articles Tagged with ''UK Biobank''

Disease architecture of the sepsis cohort generated by the Precisionlife platform

Precisionlife identifies 59 compounds based on assessment of sepsis risk genes in severe COVID-19

May 6, 2020
By Nuala Moran
LONDON – Computational biology specialist Precisionlife Ltd. has used UK Biobank data to find sepsis risk genes that are present specifically in patients who suffer severe COVID-19 infections and shown that 13 of those genes are known druggable targets.
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DNA illustration
APOE has secrets left

Large datasets, good statistics allow disease-agnostic SNP discoveries

Dec. 24, 2019
By Nuala Moran
LONDON – While large-scale biobanks that link genomics to longitudinal health records of diagnosis, treatment and outcomes promise to revolutionize the understanding of the genetics of complex disease, the detailed statistical analysis of those high-dimensional data is still very much in its infancy.
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APOE has secrets left

Large datasets, good statistics allow disease-agnostic SNP discoveries

Dec. 23, 2019
By Nuala Moran
LONDON – While large-scale biobanks that link genomics to longitudinal health records of diagnosis, treatment and outcomes promise to revolutionize understanding of the genetics of complex disease, the detailed statistical analysis of those high-dimensional data is still very much in its infancy.
Read More

Calling bias sinks CCR5 work but is 'likely unique' to variant

Oct. 15, 2019
By Nuala Moran
LONDON – A paper that raised concerns for the future health of Lulu and Nana, the world's first gene-edited babies, has been fully retracted at the request of the authors, after they failed to identify a problem in data from the U.K. Biobank on which their analysis was based. The study published in Nature Medicine in June, concluded the edits the twin girls are purported to have in their CCR5 chemokine receptor gene is associated with a 21% increase in mortality in middle and old age.
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Calling bias sinks CCR5 work but is 'likely unique' to variant

Oct. 10, 2019
By Nuala Moran
LONDON – A paper that raised concerns for the future health of Lulu and Nana, the world's first gene edited babies, has been fully retracted at the request of the authors, after they failed to identify a problem in data from the U.K. Biobank on which their analysis was based.
Read More
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