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BioWorld - Sunday, May 3, 2026
Home » central nervous system

Articles Tagged with ''central nervous system''

Eli Lilly logo atop Lilly Biotechnology Center campus in San Diego, Calif.

Ventyx’s NLRP3 inhibitors best in class? Lilly offers $1.2B

Jan. 8, 2026
By Karen Carey
No Comments
News of Eli Lilly and Co. purchasing Ventyx Biosciences Inc. for $14 per share arrived after market close Jan. 7, following unconfirmed rumors of the buyout that drove shares up by more than 52% at one point.
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Multiple sclerosis

Formation loads new Bleecker division with Lynk’s TYK2 inhibitor

Dec. 16, 2025
By Marian (YoonJee) Chu
No Comments
Formation Bio Inc. acquired ex-China rights to Lynk Pharmaceuticals Co. Ltd.’s oral TYK2-inhibitor, LNK-01006, for up to $605 million. The phase I-ready central nervous system (CNS) candidate will be developed at Formation’s newly formed subsidiary, Bleecker Bio.
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Multiple sclerosis

Formation loads new Bleecker division with Lynk’s TYK2 inhibitor

Dec. 11, 2025
By Marian (YoonJee) Chu
No Comments
Formation Bio Inc. acquired ex-China rights to Lynk Pharmaceuticals Co. Ltd.’s oral TYK2-inhibitor, LNK-01006, for up to $605 million. The phase I-ready central nervous system (CNS) candidate will be developed at Formation’s newly formed subsidiary, Bleecker Bio.
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Deal handshake with coin, chart background

ABL Bio’s Grabody lands second $2.6B deal, this time with Lilly

Nov. 13, 2025
By Marian (YoonJee) Chu
No Comments
ABL Bio Inc. inked a license and research agreement with Eli Lilly and Co. worth up to $2.6 billion to develop multiple therapeutics using the Grabody-B platform. Under the terms announced Nov. 12, ABL will receive a $40 million up-front payment and up to $2.56 billion in development, regulatory and commercialization milestones, plus tiered royalties on net sales.
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Deal handshake with coin, chart background

ABL Bio’s Grabody lands second $2.6B deal, this time with Lilly

Nov. 13, 2025
By Marian (YoonJee) Chu
No Comments
ABL Bio Inc. inked a license and research agreement with Eli Lilly and Co. worth up to $2.6 billion to develop multiple therapeutics using the Grabody-B platform. Under the terms announced Nov. 12, ABL will receive a $40 million up-front payment and up to $2.56 billion in development, regulatory and commercialization milestones, plus tiered royalties on net sales.
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Chris Lai, cofounder and CEO, Metis at Nanoforge launch

Metis plans China NDA submission for orally dissolving PBA drug

Oct. 28, 2025
By Marian (YoonJee) Chu
No Comments
Based on positive phase III study results, Metis Techbio is planning to file an NDA for its AI-derived orally disintegrating tablet drug candidate for pseudobulbar affect, MTS-004, in China next year.
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Chris Lai, cofounder and CEO, Metis at Nanoforge launch

Metis plans China NDA submission for orally dissolving PBA drug

Oct. 27, 2025
By Marian (YoonJee) Chu
No Comments
Based on positive phase III study results, Metis Techbio is planning to file an NDA for its AI-derived orally disintegrating tablet drug candidate for pseudobulbar affect, MTS-004, in China next year.
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Trimtech Therapeutics’ team
Neurology/psychiatric

UK firm Trimtech emerges with $31M seed round for TRIM21 bispecifics

March 7, 2025
By Karen Carey
Trimtech Therapeutics closed a £25 million (US$31 million) oversubscribed seed funding round to advance its targeted protein degradation treatments for neurodegenerative and inflammatory diseases.
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Trimtech Therapeutics’ team

UK firm Trimtech emerges with $31M seed round for TRIM21 bispecifics

March 5, 2025
By Karen Carey
Trimtech Therapeutics closed a £25 million (US$31 million) oversubscribed seed funding round to advance its targeted protein degradation treatments for neurodegenerative and inflammatory diseases.
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Central nervous system
Cancer

Amphista Therapeutics announces in vivo data on targeted protein degraders

Jan. 24, 2024
Amphista Therapeutics Ltd. has announced new datasets with its next-generation bifunctional protein degraders demonstrating in vivo efficacy and the ability to target and degrade proteins in the central nervous system (CNS).
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