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BioWorld - Sunday, June 21, 2026
Home » Karyopharm Therapeutics Inc.

Articles Tagged with ''Karyopharm Therapeutics Inc.''

Financial graph
Index insights

Day One buyout headlines active Q1 for cancer stocks

April 30, 2026
By Amanda Lanier
No Comments
After a standout 2025, the BioWorld Cancer Index (BCI) started 2026 on more measured footing. Early volatility this year saw the BCI drop 11.51% by the end of January before recovering to post a modest 1.39% gain for the first quarter (Q1).
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Health professional pointing stethoscope at Clinical Trial words, icons
Biopharma clinical updates March 2026

Xenon spikes, Theravance sinks after phase III readouts in March

April 28, 2026
By Amanda Lanier
No Comments
BioWorld tracked 209 clinical trial readouts across phases I through III in March 2026, up from 152 in February and 144 in January. Among late-stage programs, 26 phase III trials reported positive results, two produced mixed results, and three failed to meet key endpoints. By phase, March updates included 62 from phase I, 74 from phase II and 73 phase III.
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Health professional pointing stethoscope at Clinical Trial words, icons
Biopharma clinical updates March 2026

Xenon spikes, Theravance sinks after phase III readouts in March

April 24, 2026
By Amanda Lanier
No Comments
BioWorld tracked 209 clinical trial readouts across phases I through III in March 2026, up from 152 in February and 144 in January. Among late-stage programs, 26 phase III trials reported positive results, two produced mixed results, and three failed to meet key endpoints. By phase, March updates included 62 from phase I, 74 from phase II and 73 phase III.
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Lab sample and bone marrow illustration

Karyopharm phase III Sentry entry bucks rux in MF; to FDA next

March 24, 2026
By Randy Osborne
No Comments
What one analyst called an “intriguing” overall survival signal in phase III results has Karyopharm Therapeutics Inc. planning to meet with the U.S. FDA about a would-be sNDA filing for Xpovio (selinexor) in myelofibrosis (MF).
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Market rebound illustration
Index insights

Cancer index outperforms broader markets with 13% Q2 rebound

July 2, 2025
By Amanda Lanier
No Comments
The BioWorld Cancer Index reversed its early year losses, rebounding from a 4.74% decline at the end of the first quarter (Q1) to finish Q2 up 12.78%. The Dow Jones Industrial Average followed a similar pattern, dropping to -4.41% by the end of April before recovering to a 3.64% gain by Q2’s end. Meanwhile, the Nasdaq Biotechnology Index, down 5.37% at the end of May, narrowed its losses to close June down just 1.92%.
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Nothing misleading here, US First Circuit tells Karyopharm investors

Aug. 9, 2022
By Mari Serebrov
An investor’s wish to know more about the total landscape of a drug candidate is not enough, on its own, to make a company’s disclosures about the drug and its development materially misleading. So said the U.S. Court of Appeals for the First Circuit in affirming the dismissal of a shareholder suit against Karyopharm Therapeutics Inc. and its executive officers.
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Endometrial/uterine cancer illustration

Karyopharm plays ‘wild’ card with Xpovio in EC; pair of jacks or better?

Feb. 8, 2022
By Randy Osborne
Wall Street nicked shares of Karyopharm Therapeutics Inc. after the firm offered top-line results from the 263-subject phase III study with Xpovio (selinexor) in advanced or recurrent endometrial cancer (EC). Shares (NASDAQ:KPTI) closed at $8.19, down $2.05, or 20%, having dropped as low as $7.66.
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Green approved stamp

Antengene receives China’s first approval for oral exportin 1 inhibitor

Dec. 28, 2021
By Doris Yu
Antengene Corp. Ltd. received marketing approval from China’s NMPA for ATG-010 (selinexor), a drug that was in-licensed from Karyopharm Therapeutics Inc. It was approved for use in combination with dexamethasone to treat adults with relapsed or refractory multiple myeloma.
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Antengene receives China’s first approval for oral exportin 1 inhibitor

Dec. 22, 2021
By Doris Yu
Antengene Corp. Ltd. received marketing approval from China’s NMPA for ATG-010 (selinexor), a drug that was in-licensed from Karyopharm Therapeutics Inc. It was approved for use in combination with dexamethasone to treat adults with relapsed or refractory multiple myeloma, specifically those who have received prior therapies and whose disease is refractory to at least a proteasome inhibitor, an immunomodulatory agent and an anti-CD38 monoclonal antibody.
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Slow sales, safety signals weigh down cancer stocks, despite strong NSCLC data

Aug. 11, 2021
By Karen Carey
Contrary to the broader markets, BioWorld’s Cancer Index is down by 22% this year, losing more than 7% throughout the month of July, despite oncology driving several high-money deals and accounting for 38%, the lion’s share, of financings. Both the Nasdaq Biotech Index and the Dow Jones Industrial Average are tracking similarly for the year, and are up by 13.2% and 15.2%, respectively, as of Aug. 10.
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