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BioWorld - Monday, December 8, 2025
Home » Topics » CAR T, BioWorld Science

CAR T, BioWorld Science
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Acute myeloid leukemia illustration
Immuno-oncology

Umoja and Iaso partner to advance off-the-shelf therapies for hematological malignancies

Nov. 22, 2022
Umoja Biopharma Inc. and Nanjing Iaso Biotherapeutics Co. Ltd. have entered into a research agreement to evaluate Umoja's ICIL (induced cytotoxic innate lymphocytes) platform with Iaso's best-in-class chimeric antigen receptors (CARs).
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Cancer cells.
Immuno-oncology

Turn's technologies increase ability of T cells to kill cancer in preclinical studies

Oct. 25, 2022
Turn Biotechnologies Inc. has presented interim preclinical data that demonstrates treating T cells with its proprietary technologies can significantly increase their ability to kill cancer.
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Immuno-oncology

Oncternal's autologous CAR T therapy ONCT-808 cleared to enter clinic for aggressive B-cell NHL

Oct. 4, 2022
Oncternal Therapeutics Inc. has received IND clearance from the FDA for a phase I/II study of ONCT-808.
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Immuno-oncology

Verismo's Synkir-110 awarded US orphan drug designation for mesothelin-expressing mesotheliomas

Sep. 29, 2022
Verismo Therapeutics Inc. has received U.S. orphan drug designation from the FDA for Synkir-110 for the treatment of patients with mesothelin-expressing mesotheliomas.
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CAR T cell attacking cancer cells
Immuno-oncology

‘On’ and ‘off’ switches for CAR T-cell therapies help build safety and potency

Sep. 13, 2022
By Helen Albert
A new generation of chimeric antigen receptor (CAR) T-cell therapies with advanced functions could hold the answer to improved safety and efficacy for these effective but potentially dangerous cancer therapies, shows research led by Boston University. The scientists showed it is possible to add ‘on’ or ‘off’ switches to CAR T cells, which can be activated using oral drugs with a known safety profile.
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