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Home » Topics » Science » Microbiome

Microbiome
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Guts, glory: 'Seres' of tries in microbiome may yield success yet, experts insist

Sep. 13, 2019
By Randy Osborne
BOSTON – The gut microbiome and its prospects for drug development have been matters of debate for a while, sharpened by the high-profile phase II failure of Seres Therapeutics Inc.'s candidate, SER-109, in the summer of 2016. A panel at Biopharm America surveyed the space in light of developments since the stumble with that candidate, composed of about 50 species of firmicutes spores derived from stool specimens from healthy donors, against recurrent Clostridium difficile infection. 
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Bacterial biosensors for the gut microbiome advanced in latest work from Wyss Institute

July 2, 2019
By Stacy Lawrence
The ultimate vision is pretty fantastical: A variety of synthetically engineered bacteria working together to diagnose – and even secrete proteins to treat – various inflammatory conditions or other immune-associated diseases. But researchers at the Wyss Institute at Harvard University and Harvard Medical School have taken another step along the path toward that goal.
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