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Home » Topics » Science » Microbiome

Microbiome
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Lungs and bronchiole
Respiratory

Airway microbiome regulates chronic obstructive pulmonary disease

Aug. 30, 2022
By Mar de Miguel
A metabolite derived from the airway microbiome, indole-3-acetic acid (IAA), could become a potential therapeutic candidate for chronic obstructive pulmonary disease (COPD). Researchers at South China Normal University (SCNU) have shown how IAA prevents lung function decline by reducing inflammation, apoptosis and emphysema through IL-22 in the interaction between macrophages and alveolar epithelial cells.
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Brain teaser

Carnitine metabolite has role in cognitive aging

Dec. 31, 2021
By Anette Breindl
Investigators at the University of Freiburg and Swiss startup Ultimate Medicine have identified a compound produced by the gut microbiome as contributing to age-related cognitive decline by modulating inhibitory synaptic transmission and neural network activity.
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Atmo CEO holding capsule

Atmo raises AU$9.6M to progress ingestible capsule for analyzing the gut microbiome

Sep. 24, 2021
By Tamra Sami
PERTH, Australia – Atmo Biosciences Ltd. has closed an oversubscribed AU$9.6 million (US$7 million) capital raise that will allow it to further develop its gas-sensing capsule for monitoring the health of the gut and the microbiome. Until now, there has not been a diagnostic test that can measure gases in the gut in vivo.
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Intestine

Gut bacteria accumulate multiple therapeutic drugs

Sep. 9, 2021
By Nuala Moran
The impact that the microbiome has on drug metabolism is further elucidated in new research showing for the first time that bacteria in the gut accumulate and store drug compounds.
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Juvenile king penguin
Vultures and warthogs and bats, oh my!

Israeli startup goes bio(me)-prospecting in wild animals

March 26, 2021
By Anette Breindl
The animal world is full of species that can perform astonishing, and sometimes disgusting, feats. Take vultures, for example. “They eat this rotten meat that is full of pathogens and toxins, and they stay healthy,” Neta Raab told BioWorld. Raab is the co-founder and CEO of Wild Biotech Ltd., an Israeli startup that is seeking to understand gut microbiome contributions to these animal superpowers, and harness them for therapeutic use.
Read More
Juvenile king penguin
Vultures and warthogs and bats, oh my!

Israeli startup goes bio(me)-prospecting in wild animals

March 25, 2021
By Anette Breindl
The animal world is full of species that can perform astonishing, and sometimes disgusting, feats. Take vultures, for example. “They eat this rotten meat that is full of pathogens and toxins, and they stay healthy,” Neta Raab told BioWorld. Raab is the co-founder and CEO of Wild Biotech Ltd., an Israeli startup that is seeking to understand gut microbiome contributions to these animal superpowers, and harness them for therapeutic use.
Read More
Digital cancer cells illustration

Atlas maps cleaned-up tumor microbiomes

Dec. 31, 2020
By Anette Breindl
Researchers at Duke University have developed a set of methods to separate out microbial contamination from microbiome species that were part of tumors and used those methods to gain new insights into tumor microbiomes. 
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Microbiome illustration

Microbiome confounders research complicates control groups

Nov. 5, 2020
By Anette Breindl
Investigators at the National Institute of Allergy and Infectious Diseases have identified physiological factors that are not diseases in the narrow sense, but that nevertheless have large effects on microbiome composition.
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Startup sees opportunity to speed microbiome research

Oct. 14, 2019
By Meg Bryant
"Microbiome" has become a health and wellness buzzword, implicated as a contributing factor in conditions ranging from diabetes and obesity to gastrointestinal disease, autoimmune diseases and even autism. But the tools scientists use to cultivate bacteria have changed little over the past century, says Peter Christey, founder and CEO of San Carlos, Calif.-based startup General Automation Lab Technologies Inc. (GALT). His firm is hoping to change that with a high-throughput system of hugely parallel arrays and high-resolution images of complex samples that will revolutionize the way microbiology laboratories process genetic material.
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Harvard researchers test in vivo, fluorescent, synthetic biology microbiome tool

Oct. 14, 2019
By Stacy Lawrence
Synthetic biology is seeing rapid advances, but the medical applications have thus far remained largely elusive. But now researchers from the Wyss Institute for Biologically Inspired Engineering at Harvard University and Harvard Medical School (HMS) have developed a tool that can track specific populations of bacteria in the gut of living organisms and document population changes over time.
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