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Home » Topics » Science » RNA

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Cancer

RZ-001 shows promise for treating glioblastoma multiforme

May 15, 2024
Glioblastoma multiforme is one of the most lethal cancers; when in grade IV, patients only have a median overall survival of 14.6 months.
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3D rendering of exosomes and vesicles
Biomarkers

miRNA profiles in extracellular vesicles differentiate between ocular sarcoidosis and vitreoretinal lymphoma

May 13, 2024
Researchers from Tokyo Medical University presented data from a study that assessed microRNA (miRNA) profiles in extracellular vesicles (EVs) isolated from vitreous humor and serum of patients with ocular sarcoidosis and vitreoretinal lymphoma (VRL).
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Brain cancer illustration
Cancer

‘Onion structure’ vaccine triggers immune system against glioblastoma

May 13, 2024
By Subhasree Nag
Researchers from the University of Florida have developed a novel mRNA cancer vaccine that aims to reprogram the immune system to target and attack cancer cells effectively. The study led by Elias Sayour reported a new mRNA vaccine design where the mRNA payload was wrapped into a multilamellar vesicle within an onion-like hierarchical structure. The findings were published in the May 9, 2024 issue of Cell.
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siRNA bound to mRNA
Drug design, drug delivery & technologies

GSK selects two programs for advancement from Wave Life Sciences collaboration

April 24, 2024
Wave Life Sciences Ltd. has reported that GSK plc has selected its first two programs to advance to development candidates following achievement of target validation as part of the companies’ ongoing collaboration.
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Ribosome as part of an biological cell constructing mRNA molecules
Immuno-oncology

Curevac and MD Anderson collaborate to develop mRNA-based cancer vaccines

April 17, 2024
Curevac NV and The University of Texas MD Anderson Cancer Center have entered into a co-development and licensing agreement to develop novel mRNA-based cancer vaccines.
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Silhouette made of gears
Neurology/Psychiatric

Mina Therapeutics and Nippon Shinyaku partner on RNAa therapeutics for neurodegenerative diseases

April 5, 2024
Mina Therapeutics Ltd. has announced a research collaboration and licensing agreement option with Nippon Shinyaku Co. Ltd. for the discovery and potential development and commercialization of small activating RNA (RNAa) therapeutic candidates targeting rare neurodegenerative diseases for which there are currently no treatment options.
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Illustration of digital syringe
Drug Design, Drug Delivery & Technologies

Altamira Therapeutics and Univercells explore use of nanoparticle platform to deliver mRNA vaccines

March 26, 2024
Altamira Therapeutics Ltd. has entered into a collaboration agreement with Univercells SA to evaluate the use of the company’s proprietary Semaphore platform for the delivery of mRNA vaccines.
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Lab cultures of senescent human lung cells.
Aging

Financing at Senisca to advance senotherapeutics to treat age-related disease

March 18, 2024
Senisca Ltd., a spinout from the University of Exeter, has raised an additional £3.7 million (US$4.7 million) in funding to support the development of RNA-based senotherapeutics to treat age-related disease.
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Neurology/Psychiatric

Vect-Horus signs license agreement with Ionis to support work in neurological disease

Jan. 31, 2024
Vect-Horus SAS has entered into a license agreement providing Ionis Pharmaceuticals Inc. with a worldwide, exclusive license for a specified number of targets using Vect-Horus’ platform technology Vectrans for systemic delivery of RNA-targeted therapeutics that can cross the blood-brain barrier and address targets in the central nervous system.
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Cancer

Remix Therapeutics raises funds to advance REM-422 into clinic

Jan. 4, 2024
Remix Therapeutics Inc. has closed a $60 million financing to advance its lead program, REM-422, into the clinic and for further advancement of a pipeline of RNA processing targeted therapeutics.
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