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BioWorld - Sunday, December 21, 2025
Home » Topics » Clinical

Clinical
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Sorrento advances abivertinib for hospitalized patients, aiming for full COVID-19 cycle

July 21, 2020
By Alfred Romann

With the green light for a phase II trial to test a new drug to tackle some of the impacts of COVID-19, clinical-stage antibody developer Sorrento Therapeutics Inc. is going all in on the COVID-19 business.


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Coronavirus and syringes

Three COVID-19 vaccines generate T-cell responses

July 20, 2020
By Nuala Moran
LONDON – There were encouraging results from trials of three COVID-19 vaccines on July 20, with Astrazeneca plc, Biontech SE/Pfizer Inc. and Cansino Biologics Inc. all reporting T-cell responses in ongoing phase I/II studies of their respective products.
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Patient in hospital bed

Synairgen stock rockets as inhaled interferon-beta shows signs of efficacy in COVID-19

July 20, 2020
By Cormac Sheridan
DUBLIN – Synairgen plc has detected what appear to be promising efficacy signals in a phase II trial of its inhaled formulation of interferon-beta 1a, SNG-001, in hospitalized COVID-19 patients.
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Vials on assembly line

Celltrion starts phase I trials for COVID-19 antiviral antibody treatment CT-P59

July 20, 2020
By Gina Lee
HONG KONG – Incheon, South Korea-based Celltrion Inc. will start manufacturing its COVID-19 treatment for clinical trials and commercial distribution, even though it’s only reached phase I.
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In the clinic for July 20, 2020

July 20, 2020

Clinical updates, including trial initiations, enrollment status and data readouts and publications: Abbvie, Amplyx, Arcutis, Ascletis, Astrazeneca, Basilea, Bergenbio, Bioniz, Biontech, Bioxcel, Connect, Exelixis, Lantern, Pfizer, Synairgen, Vertex.


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Astrazeneca-Oxford COVID-19 vaccine generates rapid antibody, T-cell response

July 20, 2020
By Nuala Moran

Phage bids increasing Locus of interest as Armata cuts water

July 17, 2020
By Randy Osborne
Armata Pharmaceuticals Inc.’s recent $15 million award for a three-year program from the U.S. Department of Defense to partially fund a phase Ib/II study added to the already growing resurgence of notice for phage-based therapeutics, with even big pharma starting to take heed.
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In the clinic for July 17, 2020

July 17, 2020

Clinical updates, including trial initiations, enrollment status and data readouts and publications: ADC, Aprea, Celltrion, Janssen, Phasebio, Sinopharm.


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Antibodies attacking cancer cell

I-Mab unveils progress on novel bispecific antibody

July 16, 2020
By David Ho
HONG KONG – Shanghai-based I-Mab Biopharma Co. Ltd. expects to begin clinical trials for the world’s first and only claudin18.2 and 4-1BB bispecific program in a year. "We expect the trial to start in U.S. in the [middle of] next year. We will then expand the trial to China afterwards as planned," Joan Shen, CEO of I-Mab, told BioWorld.
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In the clinic for July 16, 2020

July 16, 2020

Clinical updates, including trial initiations, enrollment status and data readouts and publications: AC, Algernon, Aprea, Arcutis, Astrazeneca, Calcimedica, Fab'entech, Heron, Ideaya, Neurorx, Oncorus, Relief, Rhythm, Santen.


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