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BioWorld - Tuesday, May 12, 2026
Home » Topics » Clinical

Clinical
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Immutep reports positive interim phase II results in Keytruda combo basket trial

March 3, 2020
By Tamra Sami
PERTH, Australia – Immutep Ltd. reported positive interim data for its phase II basket trial in non-small-cell lung cancer and head and neck squamous cell carcinoma for its lead immunotherapy in combination with Merck & Co. Inc.’s Keytruda (pembrolizumab).
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Rays of light beaming from eye

After some trying times, AGTC ‘night star’ on the rise in XLRP and beyond

March 3, 2020
By Randy Osborne
Strongly favorable six-month data disclosed on Jan. 9 by Applied Genetic Technologies Corp. (AGTC) from its ongoing phase I/II program with an adeno-associated virus (AAV) gene therapy for X-linked retinitis pigmentosa (XLRP) did more than provide a whopping stock boost.


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Cool beans: Boston phase III exportin success to broader Xpovio label?

March 3, 2020
By Randy Osborne
With new phase III multiple myeloma (MM) data in hand from Newton, Mass.-based Karyopharm Therapeutics Inc.’s Xpovio (selinexor), Wall Street began speculating about what the results might mean in the marketplace.
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Cancer cell, DNA illustration

Todos Medical sets sights on COVID-19 test market

March 2, 2020
By Meg Bryant
New York and Rehovot, Israel-based in vitro diagnostics startup Todos Medical Ltd. is developing blood tests for the early detection of cancer and neurodegenerative diseases using Fourier-transform infrared (FTIR) spectroscopy. Now the company is looking to apply the technology in diagnosing infections, including the novel coronavirus, COVID-19.
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2-28-onduo-diabetes.png

Diabetes tech use still limited, but the latest data aims to broaden CGM, closed loop reach

Feb. 28, 2020
By Stacy Lawrence
Over the last few years, Wall Street has fervently embraced the largest diabetes technology companies, particularly those behind continuous glucose monitors, insulin pumps, and the automated closed loop systems that incorporate both to work together.
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Livanova teams up with Verily on depression trial

Feb. 27, 2020
By Meg Bryant
London-based Livanova plc has entered a collaboration with Verily Inc., an Alphabet company, to enrich data from its RECOVER trial using tools and analytics developed by Verily. The study, which kicked off last September, is assessing the effectiveness of vagus nerve stimulation (VNS) therapy for patients with difficult-to-treat depression (DTD).
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T cells

TIGIT-al camera snapshot shows cancer bids fill the frame

Feb. 27, 2020
By Randy Osborne
During a recent investor event related to early drug development, Basel, Switzerland-based Roche Holding AG touted research by the firm’s Genentech unit into the cancer target known as TIGIT, or T-cell immunoreceptor with Ig and ITIM domains, and the pharma giant is hardly alone in the sizzling space.
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Kadmon TCT data provide ‘Incyte,’ GVHD odds looking better

Feb. 27, 2020
By Randy Osborne
New York-based Kadmon Holdings Inc.’s recent oral late-breaker session on KD-025 in chronic graft-vs.-host disease (cGVHD) at the Transplantation & Cellular Therapy (TCT) meeting – along with data that rolled out from two studies testing competitor Jakafi (ruxolitinib) from Incyte Corp. – signaled potential advantages in the former’s candidate, already highly regarded.
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Small study finds AI gets patients to stroke treatment faster, as 500-patient study to start

Feb. 26, 2020
By Stacy Lawrence
Artificial intelligence still has a lot to prove when it comes to its relevance in improving health care. But one bright spot was a deal last July between Dublin-based Medtronic plc and San Francisco-based startup Viz.ai Inc. to use the latter’s AI system that’s designed to spot a large vessel occlusion automatically in CT angiogram images.
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Menlo, Vanda see mixed results after missing primary endpoints in pruritus trials

Feb. 26, 2020
By Michael Fitzhugh
Readouts from two ambitious pruritus trials this week yielded starkly different reactions from investors seeking broader meaning in the outcomes.
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