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BioWorld - Sunday, June 7, 2026
Home » Topics » Conferences » European Society for Medical Oncology

European Society for Medical Oncology
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Breast cancer illustration
Cancer

USP1 inhibitor VRTX-531 shows antitumor activity in BRCA1-mutated and HRD+ tumors

May 17, 2024
Vrise Therapeutics Inc. has developed and presented a USP1 inhibitor, VRTX-531, for the potential treatment of BRCA1/2-mutated HDR+ breast cancer.
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MSD, Roche highlight new sub analysis data at ESMO Asia in Asia-prevalent cancers

Jan. 2, 2024
By Tamra Sami
MSD had a banner year at the ESMO Asia Congress earlier this month, presenting 14 abstracts on eight different types of cancers, including gastric, esophageal, colorectal, biliary tract, kidney, urothelial, breast and gynecological cancers. Ten of these studies were focused on Asian-related data. Roche AG, meanwhile, presented Asia-specific results from the phase III Alina study in patients with ALK-positive early stage non-small-cell lung cancer.
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MSD, Roche highlight new sub analysis data at ESMO Asia in Asia-prevalent cancers

Dec. 28, 2023
By Tamra Sami
MSD had a banner year at the ESMO Asia Congress earlier this month, presenting 14 abstracts on eight different types of cancers, including gastric, esophageal, colorectal, biliary tract, kidney, urothelial, breast and gynecological cancers. Ten of these studies were focused on Asian-related data. Roche AG, meanwhile, presented Asia-specific results from the phase III Alina study in patients with ALK-positive early stage non-small-cell lung cancer.
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3D illustration demonstrating antibody-drug conjugate.
Immuno-oncology

ARX-305 demonstrates promising PK, efficacy and safety profile in preclinical models

Nov. 8, 2023
Researchers from Ambrx Inc. and Novocodex Biopharmaceuticals Co. Ltd. presented preclinical data for ARX-305, a next-generation anti-CD70 antibody-drug conjugate (ADC), being developed for the treatment of CD70-expressing cancers.
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3D representation of tumor microenvironment
Immuno-oncology

Combining optimal affinity rTCRs with PD1-41BB CSP protects against TME immunosuppression

Nov. 2, 2023
Researchers from Medigene AG recently presented the discovery and preclinical evaluation of first-in-class, third-generation T-cell receptor T-cell (TCR-T) therapies, MDG-1015 and MDG-2011.
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Antibodies attacking cancer cell
Immuno-oncology

EpCAMx4-1BB demonstrates conditional agonistic and antitumor activity

Oct. 31, 2023
Researchers from Biontech SE and Genmab BV presented the discovery and preclinical evaluation of a novel Duobody-EpCAMx4-1BB (BNT314/GEN1059), a novel Fc-inert immunomodulatory bispecific antibody (bsAb) designed to boost antitumor immune responses through EpCAM-dependent 4-1BB agonistic activity.
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Cancer

HLX-42 is EGFR-targeting ADC with activity in several cancer models

Oct. 31, 2023
Researchers from Shanghai Henlius Biotech Inc. presented the discovery and preclinical characterization of HLX-42, a next-generation EGFR-targeting antibody-drug conjugate (ADC) being developed for the treatment of cancer.
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Antibody-drug conjugate illustration
Immuno-oncology

HLX-43, a next-generation PD-L1-targeting antibody-drug conjugate

Oct. 27, 2023
There is a need for new agents targeting PD-1/PD-L1 because many patients either do not respond or develop resistance to treatment.
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Cancer

EXS-74539 demonstrates efficacy in primary AML patient tissue samples

Oct. 27, 2023
Researchers from Exscientia plc presented preclinical data for the novel reversible LSD1 inhibitor EXS-74539, being developed as a monotherapy or in combination with standard of care for the treatment of oncology and hematology indications including acute myeloid leukemia (AML) and small-cell lung cancer.
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Female reproductive system and cancer cells

ESMO 2023: Latest advances in gynecological cancer

Oct. 25, 2023
By Mar de Miguel
The Congress of the European Society of Medical Oncology (ESMO) held in Madrid from Oct. 20 to 24, 2023, could well add the letter W to its acronym after the four sessions on gynecological cancer that could represent a milestone in the lives of all women who suffer from cervical, ovarian, or endometrial cancer.
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