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BioWorld - Monday, December 15, 2025
Home » Topics » Deals and M&A

Deals and M&A
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Handshake with dollar sign and checkmark

Skyhawk’s small-molecule RNA efforts draw Merck KGaA in $2B deal

Aug. 18, 2025
By Jennifer Boggs
No Comments
Adding another name to an impressive roster of partners assembled over the past few years, Skyhawk Therapeutics Inc. inked a neurology-focused deal with Merck KGaA aimed at discovering small-molecule RNA-targeted drugs that could be worth more than $2 billion.
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Cardiovascular illustration
Endocrine/metabolic

Superluminal joins a $1.3B deal with series A backer Lilly

Aug. 18, 2025
By Lee Landenberger
No Comments
Superluminal Medicines Inc. and Eli Lilly and Co. are collaborating in a deal to develop cardiometabolic disease and obesity therapies by aiming at undisclosed G protein-coupled receptor targets. The deal could bring Superluminal as much as $1.3 billion, including up-front and near-term investments, an equity investment, development and commercial milestones, plus tiered royalties on net sales.
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Immuno-oncology

Grant supports Cptx and Nanocell’s in vivo CAR T therapy project

Aug. 18, 2025
No Comments
Cptx GmbH’s QUIET-CAR collaborative project with Nanocell Therapeutics Inc. has been awarded a Eurostars Grant from the EU through the Horizon Europe program and Eureka Network. The QUIET-CAR project aims to develop targeted lipid nanoparticles carrying novel immune-silent single-stranded DNA (ssDNA) for in vivo CAR T therapy.
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Lumos Febridx
Med-tech deals July 2025

Lumos scores top July deal in subdued med-tech market

Aug. 15, 2025
By Amanda Lanier
Reported med-tech deal value in the first seven months of 2025 remained sharply subdued, totaling just $657.44 million across all non-M&A transactions, a fraction of the $1.24 billion reported by this time last year. The current total is the lowest for any January-to-July period in the past seven years, though less than 2% of deals disclosed dollar values. 
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Biopharma deals July 2025

Biopharma sees fewer deals but much bigger dollars

Aug. 15, 2025
By Amanda Lanier
No Comments
Biopharma deal activity (excluding M&As) has surged to record-breaking levels in the first seven months of 2025, reaching $164.03 billion, well above prior years and a 36% jump over the same period in 2024.
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Cardiovascular illustration

Superluminal joins a $1.3B deal with series A backer Lilly

Aug. 14, 2025
By Lee Landenberger
No Comments
Superluminal Medicines Inc. and Eli Lilly and Co. are collaborating in a deal to develop cardiometabolic disease and obesity therapies by aiming at undisclosed G protein-coupled receptor targets. The deal could bring Superluminal as much as $1.3 billion, including up-front and near-term investments, an equity investment, development and commercial milestones, plus tiered royalties on net sales.
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Lung cancer driven by the Kras oncogene shown in purple
Cancer

Bayer and Kumquat sign deal for KRAS G12D inhibitor

Aug. 13, 2025
No Comments
Bayer AG and Kumquat Biosciences Inc. have entered into an exclusive global license and collaboration agreement to develop and commercialize Kumquat’s KRAS G12D inhibitor.
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Hands holding arrow-shaped puzzle pieces

Deephealth closes $110M Icad buy, gains Techlive clearance

Aug. 12, 2025
By Annette Boyle
Deephealth Inc., a subsidiary of Radnet Inc., completed the acquisition of breast health solutions company Icad Inc. in a $110 million all-stock transaction. The company also received U.S. FDA 510(k) clearance for Techlive – a remote scanning solution enabling centralized operation and supervision of MR, CT, PET/CT and ultrasound procedures.
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Gregory Verdine, founder and CEO, Dovetree

Xtalpi finalizes $6B AI drug discovery deal with Dovetree

Aug. 12, 2025
By Marian (YoonJee) Chu
No Comments
Quantumpharm Inc., known as Xtalpi Inc., announced receiving $51 million up front from a potential $5.99 billion deal with Dovetree LLC on Aug. 6. The collaboration, first inked through a letter of intent between the two parties on June 23, will combine Shenzhen, China-based Xtalpi’s AI-based and robotics-driven discovery platform with Dovetree’s “biological insights.” The goal will be to select and validate potential first-in-class candidates for Dovetree across five areas of oncology, immunology and inflammatory diseases, neurological disorders and metabolic dysregulation.
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Lungs

Fosun out-licenses phase II DPP-1 to newco Expedition for $645M

Aug. 12, 2025
By Tamra Sami
No Comments
Fosun Pharmaceutical Co. Ltd. subsidiary Fosun Pharma Industrial is out-licensing its phase II dipeptidyl peptidase 1 inhibitor, XH-S004, to newco Expedition Therapeutics Inc. in a deal worth up to $645 million. Under terms of the deal, Expedition gains global rights to rights to develop, manufacture and commercialize XH-S004, except in mainland China, Hong Kong and Macau.
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