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BioWorld - Wednesday, January 14, 2026
Home » Topics » Disease categories and therapies » Cardiovascular

Cardiovascular
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Transthera raises $38M, propelling TT-0420 toward market

Feb. 28, 2023
By Doris Yu
Transthera Sciences Inc., a Nanjing, China-based company developing small-molecule therapies in cancer, inflammation and cardiovascular disease, raised ¥260 million (US$38 million) in a series D+ funding round to advance its first drug product.
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Yen-Yuan symbols

Transthera raises $38M, propelling TT-0420 toward market

Feb. 27, 2023
By Doris Yu
Transthera Sciences Inc., a Nanjing, China-based company developing small-molecule therapies in cancer, inflammation and cardiovascular disease, raised ¥260 million (US$38 million) in a series D+ funding round to advance its first drug product.
Read More
Heart scientific overlay
Cardiovascular

Actelion Pharmaceuticals discovers new PDGFR inhibitors

Feb. 27, 2023
Actelion Pharmaceuticals Ltd. has disclosed platelet-derived growth factor receptor beta (PDGFR-β) inhibitors reported to be useful for the treatment of pulmonary arterial hypertension.
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Locket device placed after surgery

Merged firms seek lock down of percutaneous wound market with suture holding device

Feb. 24, 2023
By David Godkin
Ra Medical Systems Inc. launched a simple device that holds sutures more securely in place for closure of percutaneous wound sites during cardiac electrophysiology, structural heart and vascular surgical procedures.
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Illustration of Aurora EV-ICD in chest

Medtronic CE mark receipt strengthens cardiac rhythm business

Feb. 24, 2023
By Shani Alexander
Medtronic plc recently received the CE mark for its Aurora extravascular implantable cardioverter-defibrillator (EV-ICD) strengthening its cardiovascular portfolio which saw a 7% year-on-year growth in the third quarter of its fiscal year 2023.
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Heart and DNA
Biomarkers

Rs2019090 polymorphism tied to coronary artery disease risk

Feb. 24, 2023
Coronary artery disease (CAD) will likely remain the worldwide leading cause of death for the next couple of decades. Genome-wide association studies (GWAS) have been useful to identify hundreds of genomic loci that contribute CAD risk.
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Xeltis completes $34M funding round for polymer implant development

Feb. 23, 2023
By Nuala Moran
Xeltis BV has completed a €32 million (US$34 million) series D2 round that will propel the clinical development of its electrospun polymer implants across several indications. The fully synthetic implants promise the best of both worlds, with the mechanical strength required to be fully functional from day one, and bioresorbable properties that cause gradual degradation as endogenous tissue regenerates to form a natural replacement.
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Cardiovascular

Zoetis Services discovers 5-HT2B receptor antagonists for heart failure

Feb. 23, 2023
Zoetis Services LLC has described 5-HT2B receptor antagonists reported to be useful for the treatment of heart failure.
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3D illustration of heart cross section
Cardiovascular

Preclinical profile of novel cardiac myosin inhibitor CK-586 disclosed

Feb. 23, 2023
Hypertrophic cardiomyopathy (HCM) is an inherited disorder where different mutations in cardiac myosin lead to hypercontractility of...
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Blood clot blocking a blood vessel
Cardiovascular

BB-031, a new aptamer inhibitor of VWF with efficacy in canine large vessel occlusion stroke model

Feb. 16, 2023
Researchers from Basking Biosciences Inc. presented preclinical data for BB-031, a novel RNA aptamer that binds and inhibits Von Willebrand Factor (VWF). BB-031 (0.5, 1.0 and 5.0 mg/kg) or placebo were administered to a canine model of large vessel occlusion (LVO) stroke at 6 hours post-LVO with an autologous clot.
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