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BioWorld - Wednesday, January 7, 2026
Home » Topics » Disease categories and therapies » Cardiovascular

Cardiovascular
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APACMed Forum 2024

APAC seen as opportunity zone to change health care

Sep. 6, 2024
By Tamra Sami
Asia Pacific is the fastest growing region for health care spending, and by 2030 APAC will account for more than 20% of global health care spending, Tom Lawry, managing director of Second Century Tech told the APACMed Forum 2024 conference held in Singapore, Sept 5-6.
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AI-generated illustration of heart and metabolic impact

Angiodynamics receives CE mark for Auryon atherectomy system

Sep. 6, 2024
By Shani Alexander
Angiodynamics Inc. received CE mark approval for its Auryon atherectomy system which treats peripheral artery disease, including critical limb ischemia and in-stent restenosis. The regulatory clearance expands the company’s global reach as it sees increasing revenues from sales of the device.
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Illustration of heart and lung vasculature in pulmonary hypertension vs. normal
Cardiovascular

Effect of COR-1389 on cardiopulmonary function in pulmonary hypertension associated with right heart failure

Sep. 6, 2024
Researchers from Corteria Pharmaceuticals SAS and Université Paris-Saclay recently presented the preclinical results on a long-acting corticotropin-releasing factor CRF2 receptor agonist, COR-1389.
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Glenmark settles US civil price-fixing allegations

Sep. 5, 2024
Glenmark Pharmaceuticals Inc. USA agreed Sept. 4 to pay $25 million, based on its ability to pay, to resolve the Department of Justice’s civil allegations that it conspired to fix the U.S. price of pravastatin, a generic drug used to treat high cholesterol.
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3D illustration of heart cross section

ESC-ape velocity? Cytokinetics revs HCM case with aficamten

Sep. 5, 2024
By Randy Osborne
Cytokinetics Inc. CEO Robert Blum said his firm chalked “a watershed moment” during last weekend’s congress of European Society of Cardiology (ESC) in London, where further mid- and late-stage data were disclosed with the heart drug aficamten, a myosin inhibitor. South San Francisco-based Cytokinetics rolled out six presentations, including two late breakers, with four concurrent publications in medical journals.
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Dynamx coronary bioadaptor system

Elixir’s Dynamx bioadaptor meets primary endpoint

Sep. 5, 2024
By Shani Alexander
Elixir Medical Corp. reported positive 12-month data from the Infinity-Swedeheart trial that compared its Dynamx coronary bioadaptor system to Medtronic plc’s Resolute Onyx zotarolimus drug-eluting stent in patients requiring percutaneous coronary intervention with coronary artery disease.
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Varleriot vein harvesting device
Patents

No-touch vein harvesting device for coronary artery bypass surgery

Sep. 5, 2024
By Simon Kerton
In what represents Vienna, Austria-based Valeriot GmbH’s first patenting, its founder and CEO, Michael Flatscher, describes their invention of a device, Autovein, for use in no-touch vein harvesting which overcomes the issues faced with traditional vein harvesting techniques which are laborious, prone to complications and challenging to master.
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Cardiovascular

Nanjing Huanbo Biotechnology patents new GRK2 degradation inducers for PAH

Sep. 5, 2024
Nanjing Huanbo Biotechnology Co. Ltd. has disclosed proteolysis targeting chimeras (PROTACs) comprising an E3 ubiquitin ligase binding agent coupled to a β-adrenergic receptor kinase 1 (BARK1; GRK2) targeting moiety via a linker acting as GRK2 degradation inducers.
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Man clutching heart
Cardiovascular

Pfizer presents data on PF-07328948 for the treatment of heart failure

Sep. 5, 2024
Essential branched-chain amino acids (BCAA) such as leucine, isoleucine or valine, cannot be synthesized by mammals, making them an obligate part of the diet.
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Heart scientific overlay
Cardiovascular

AZD-0780 lowers LDL-C plasma levels by stabilizing the PCSK9 C-terminal domain

Sep. 5, 2024
Researchers from Astrazeneca plc presented the structure and preclinical characterization of a novel PCSK9 inhibitor, AZD-0780, being developed for the treatment of cardiovascular disease. A new potentially druggable functional binding pocket was identified on the PCSK9 C-terminal domain (CTD), and multiple fragment screens generated a single CTD-binding hit.
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