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BioWorld - Saturday, April 11, 2026
Home » Topics » Disease categories and therapies » Cardiovascular

Cardiovascular
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Heart and DNA
Biomarkers

Genome-wide analysis identifies loci tied to atrial septal defects

June 12, 2024
Atrial septal defect (ASD) is a congenital heart condition where the formation of the connection between the atrial chambers is defective, thus allowing left-to-right shunting and the consequent risk of atrial fibrillation, stroke and heart failure, among others.
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Seers

AI-wearable, telehealth firm Seers Technology upsizes Kosdaq IPO

June 11, 2024
By Marian (YoonJee) Chu
South Korean digital health care firm Seers Technology Co. Ltd. is targeting a ₩22.1 billion (US$16.2 million) IPO on the Korea Exchange, after upping the offering price of its 1.3 million shares to ₩17,000 per share on June 4.
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Single Shot PVI

Kardium enters pulsed field ablation market with $104M financing

June 11, 2024
By Annette Boyle
Kardium Inc. landed $104 million in new financing for its Globe mapping and ablation system for atrial fibrillation, positioning it to enter the rapidly changing field in the U.S. The funds will allow the company to finish its PULSAR trial, secure FDA approval and launch its pulsed field ablation system commercially, Kardium Chief Financial Officer Koert VandenEnden told BioWorld.
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DeepQure

Deepqure gets FDA IDE nod for renal denervation device trial

June 11, 2024
By Marian (YoonJee) Chu
As renal denervation (RDN) makes a comeback for treatment-resistant hypertension, Deepqure Inc. is advancing its RDN medical device dubbed Hyperqure with the U.S. FDA granting clearance for a U.S.-based study.
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Spinal cord
Neurology/psychiatric

Two different cells cause fibrosis after traumatic CNS injury

June 11, 2024
By Mar de Miguel
Scientists from the Karolinska Institute have found two different types of cells that give rise to the fibroblasts that form fibrotic scars after spinal cord injury (SCI) depending on their location. In a study in mice, the researchers observed that pericytes acted in lesions that affect the gray matter and perivascular fibroblasts acted in the white matter.
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Biomarkers

New clinical entity associated with PIK3R1 and PIK3CA variants

June 10, 2024
Scientists at de Duve Institute focused on the genetic causes of vascular anomalies, more specifically on capillary malformation with dilated veins (CMDV).
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Seers

AI-wearable, telehealth firm Seers Technology upsizes Kosdaq IPO

June 7, 2024
By Marian (YoonJee) Chu
South Korean digital health care firm Seers Technology Co. Ltd. is targeting a ₩22.1 billion (US$16.2 million) IPO on the Korea Exchange, after upping the offering price of its 1.3 million shares to ₩17,000 per share on June 4.
Read More
Device in heart

Edwards offers SMART defense with data showing positive small annulus outcomes

June 6, 2024
By Holland Johnson
In what undoubtedly came as a response to Medtronic plc’s recently reported Small Annuli Randomized to Evolut or SAPIEN Trial trial results that showed a decisive advantage for its Evolut transcatheter aortic valve replacement system in patients with a small aortic annulus, Edwards Lifesciences Corp. reported the results from an analysis of data from its Placement of Aortic Transcatheter Valve trials of the Sapien 3 valves showing “excellent clinical outcomes and valve durability irrespective of the patient’s annulus size or sex.”
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Cancer

Relay Therapeutics discloses new genetic disease and oncology programs

June 6, 2024
Relay Therapeutics Inc. has disclosed three new programs from its existing preclinical pipeline, including two novel programs from its genetic disease portfolio and a potentially first-in-class NRAS-selective inhibitor.
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Acquisition puzzle

Edwards forgoes critical care spin, sells unit to BD for $4.2B

June 3, 2024
By Holland Johnson
Edwards Lifesciences Corp. is selling its critical care product group to Becton Dickison and Co. (BD) for $4.2 billion in cash, forgoing its previously announced plans to spin off the unit into a separate business. The transaction is expected to close before the end of the calendar year.
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