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BioWorld - Saturday, June 20, 2026
Home » Topics » Endocrine/metabolic, BioWorld Science

Endocrine/metabolic, BioWorld Science
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Hepatitis B virus
Drug Design, Drug Delivery & Technologies

Precision Biosciences outlines pipeline progress

Sep. 12, 2023
Precision Biosciences Inc. uses its proprietary Arcus platform to develop in vivo gene editing therapies and has outlined new data from its wholly owned and partnered pipeline.
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Heart with blocked arteries
Cardiovascular

YN-001 demonstrates good safety profile and excellent efficacy in mouse model of atherosclerosis

Sep. 8, 2023
Researchers from Beijing Inno Medicine Co. Ltd. recently reported preclinical data for the novel liposome encapsulated rosuvastatin calcium candidate, YN-001, being developed for the treatment of atherosclerosis.
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Endocrine/Metabolic

Beam presents first preclinical data for BEAM-302 from in vivo rodent models of AATD

Sep. 8, 2023
Beam Therapeutics Inc. has released new preclinical data demonstrating the ability of its in vivo drug candidate, BEAM-302, to directly correct the PiZ mutation, the primary disease-causing mutation associated with severe α1-antitrypsin deficiency (AATD).
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Endocrine/Metabolic

Novartis divulges new GLP-1R agonists

Sep. 7, 2023
Novartis AG has synthesized glucagon-like peptide 1 receptor (GLP-1R) agonists reported to be useful for the treatment of type 2 diabetes, obesity, hypertension, stroke, hyperglycemia, dyslipidemia, nonalcoholic steatohepatitis and diabetic nephropathy, among others.
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Endocrine/Metabolic

Broad Institute and Novo Nordisk collaborate in type 2 diabetes and cardiac fibrosis

Sep. 7, 2023
The Broad Institute of MIT and Harvard has announced a new research alliance with Novo Nordisk A/S in diabetes and cardiometabolic diseases. The collaboration will focus on advancing three programs over the next 3 years.
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Thymus
Immune

The human thymus has multipotent stem cells with the capacity to maintain it

Sep. 7, 2023
By Mar de Miguel
It was believed that they did not exist, but they are a reality. Scientists at the Francis Crick Institute in London have discovered stem cells in the thymus for the first time. The last organ to have its role described in humans still has properties that researchers could explore to prevent the decline of the immune system throughout life.
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RNA strand
Endocrine/Metabolic

Wave submits CTA for WVE-006 for α1-antitrypsin deficiency

Sep. 6, 2023
Wave Life Sciences Ltd. has submitted its first clinical trial application (CTA) for WVE-006 for α1-antitrypsin deficiency (AATD).
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Endocrine/Metabolic

Madrigal Pharmaceuticals presents new THR-β agonists

Sep. 5, 2023
Madrigal Pharmaceuticals Inc. has divulged thyroid hormone receptor β (THR-β) agonists reported to be useful for the treatment of familial hypercholesterolemia, hyperlipidemia, hypertriglyceridemia and nonalcoholic steatohepatitis.
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Endocrine/Metabolic

Gasherbrum Bio describes new GLP-1R agonists

Sep. 5, 2023
Gasherbrum Bio Inc. has identified glucagon-like peptide 1 receptor (GLP-1R) agonists reported to be useful for the treatment of type 2 diabetes, dyslipidemia, hyperglycemia, hypertension, obesity, stroke, myocardial infarction and gout, among others.
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Test tubes, dropper and capsules
Endocrine/Metabolic

Krystal Biotech’s KB-408 awarded US orphan drug designation for AATD

Sep. 5, 2023
The FDA has awarded orphan drug designation to Krystal Biotech Inc.’s KB-408 for the treatment of α1-antitrypsin deficiency (AATD).
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