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BioWorld - Thursday, March 26, 2026
Home » Topics » Disease categories and therapies » Genitourinary/sexual function

Genitourinary/sexual function
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China greenlights Salubris’ HIF-PH inhibitor for anemia

June 27, 2023
By Doris Yu
Shenzhen Salubris Pharmaceuticals Co. Ltd. received marketing approval from China’s NMPA for enarodustat as a treatment for anemic patients with chronic kidney disease that are not on dialysis.
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Urinary tract with kidneys, adrenalin glands, ureter and vessels on light blue background

Telix expands urology pipeline with $35M acquisition of Lightpoint Medical

June 27, 2023
By Tamra Sami
Telix Pharmaceuticals Ltd. will acquire Lightpoint Medical Ltd. in a $35 million deal that will expand its urology pipeline and bring in house a new surgery-focused unit. Under the terms of the deal, Telix of Melbourne, Australia, will pay Lightpoint $20 million up front and a further $15 million on achievement of certain development milestones. The up-front payment will be paid in equity, and the additional milestones will be payable in cash or equity, at Telix’s election.
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Endometriosis saliva test

Ziwig’s spit test is spot on for endometriosis

June 23, 2023
By Bernard Banga
Difficulty in obtaining an accurate diagnosis and treatment for endometriosis leaves many women spitting mad, but they may soon find that saliva is the key to escaping the diagnostic maze. A recent study published in the New England Journal of Medicine validated the Endotest developed by Ziwig SAS based on results from a study involving 200 symptomatic patients monitored in five hospital units and specialized centers in France since November 2021. The findings demonstrated a sensitivity and specificity of more than 95%.
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Urinary tract with kidneys, adrenalin glands, ureter and vessels on light blue background

Telix expands urology pipeline with $35M acquisition of Lightpoint Medical

June 22, 2023
By Tamra Sami
Telix Pharmaceuticals Ltd. will acquire Lightpoint Medical Ltd. in a $35 million deal that will expand its urology pipeline and bring in house a new surgery-focused unit. Under the terms of the deal, Telix of Melbourne, Australia, will pay Lightpoint $20 million up front and a further $15 million on achievement of certain development milestones. The up-front payment will be paid in equity, and the additional milestones will be payable in cash or equity, at Telix’s election.
Read More
General Stim implanted sacral nerve stimulation system

General Stim’s implanted sacral nerve stimulation approved in China

June 16, 2023
By Doris Yu
General Stim Inc.’s implanted sacral nerve stimulation (SNS) system was approved in China to treat individuals with certain bladder and bowel conditions. Hangzhou-based General Stim’s SNS system consists of a sacral nerve stimulator, an extension lead and an electrode.
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Endometriosis
Genitourinary/Sexual Function

Study indicates a bacterium could be one cause of endometriosis, suggesting antibiotics are a potential treatment

June 16, 2023
By Mar de Miguel
A new study has shown that a uterine bacterium is one cause of endometriosis and that preventing the infection could prevent development of the pathology, in which tissue similar to the lining of the uterus grows in the abdominal cavity.
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Kidneys

Novartis gets its hooks in Chinook with $3.5B offer

June 12, 2023
By Caroline Richards
On a quest to boost its renal diseases pipeline with two late-stage drugs, Novartis AG has announced plans to acquire precision medicines drug developer Chinook Therapeutics Inc., offering up to $3.5 billion. The move drove Chinook’s shares (NASDAQ:KDNY) up by 58.3%, or $13.99, on June 12, closing at $37.98.
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Genitourinary/Sexual Function

New Far1 KO mouse model unveils the essential role of ether lipids in spermatogenesis

May 31, 2023
Ether lipids (EL) are glycerophospholipids with a different structure and functional characteristics than fatty acids, thus requiring a specialized biosynthesis pathway. Peroxisomal fatty acyl-CoA reductase 1 (FAR1) is a rate-limiting enzyme for ether lipid synthesis, with mutations associated with a rare human disease. Moreover, altered EL homeostasis has been observed in various prevalent human diseases.
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Bladder of a mouse that was reinfected with E. coli
Genitourinary/Sexual Function

Memory T cells control immunity to urinary reinfection

May 31, 2023
By Mar de Miguel
Urinary tract infections (UTIs) are often recurrent. The organism does not always establish an effective line of defense that protects from reinfection. The key lies in two reservoirs of bacteria and how tissue-resident memory T cells (TRMs) trigger the immune response. A recent paper from the Pasteur Institute in France describes how these cells mediate immunity to defeat reinfection.
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Rona and Keymed partner to develop siRNA therapies for severe kidney diseases

May 23, 2023
By Tamra Sami
Rona Therapeutics Co. Ltd. and Keymed Biosciences Co. Ltd. formed a collaboration to jointly discover and develop first-in-class siRNA therapeutics for glomerulonephritis, also known as severe kidney diseases.
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