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BioWorld - Monday, April 20, 2026
Home » Topics » Disease categories and therapies » Inflammatory

Inflammatory
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Inflammatory

Insilico Medicine patents new NLRP3 inflammasome inhibitors

Dec. 18, 2024
Insilico Medicine Inc. has disclosed NLRP3 inflammasome inhibitors reported to be useful for the treatment of autoimmune and inflammatory disorders.
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Man measuring waist

Caliway’s CBL-514 meets endpoints in reducing abdominal fat

Dec. 17, 2024
By Tamra Sami
Caliway Biopharmaceuticals’ lipolysis candidate, CBL-514, met all the primary and secondary efficacy endpoints in a phase IIb study for subcutaneous fat reduction, paving the way for the company to begin a global pivotal phase III study in 2025.
Read More
T cells

Candid, Epimab ink $1B T-cell engager deal in autoimmune disease

Dec. 17, 2024
By Tamra Sami
Candid Therapeutics Inc. and Epimab Biotherapeutics Inc. have entered a $1 billion research collaboration to discover and develop novel T-cell engager candidates for autoimmune indications.
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Concept of business partnership

Relation inks two GSK deals tackling osteoarthritis, fibrotic disease

Dec. 12, 2024
By Nuala Moran
Relation Therapeutics Ltd. has delivered the first commercial validation of its combined wet lab/in silico platform for homing in on disease-related genes in the thick of the genome, signing two collaboration agreements with GSK plc, with a potential value of $200 million per target.
Read More
Man measuring waist

Caliway’s CBL-514 meets endpoints in reducing abdominal fat

Dec. 12, 2024
By Tamra Sami
Caliway Biopharmaceuticals’ lipolysis candidate, CBL-514, met all the primary and secondary efficacy endpoints in a phase IIb study for subcutaneous fat reduction, paving the way for the company to begin a global pivotal phase III study in 2025.
Read More
Ear illustration

Loud and clear: Sound Pharma has phase III success in Meniere’s

Dec. 11, 2024
By Lee Landenberger
Sound Pharmaceuticals Inc.’s lead candidate, the anti-inflammatory SPI-1005 (ebselen), has produced positive pivotal phase III study data in treating Meniere’s disease, an inner-ear disorder that can lead to vertigo and deafness.
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Concept of business partnership
Inflammatory

Relation inks two GSK deals tackling osteoarthritis, fibrotic disease

Dec. 11, 2024
By Nuala Moran
Relation Therapeutics Ltd. has delivered the first commercial validation of its combined wet lab/in silico platform for homing in on disease-related genes in the thick of the genome, signing two collaboration agreements with GSK plc, with a potential value of $200 million per target.
Read More

Paradigm's AU$16M moves Zilosul to pivotal osteoarthritis trials

Dec. 10, 2024
By Tamra Sami
Paradigm Biopharmaceuticals Ltd. raised AU$16 million (US$10.31 million) in a placement that will allow the company to start a global phase III trial with its lead product, Zilosul (injectable pentosan polysulfate/iPPS), to treat osteoarthritis.
Read More
Concept of business partnership

Relation inks two GSK deals tackling osteoarthritis, fibrotic disease

Dec. 10, 2024
By Nuala Moran
Relation Therapeutics Ltd. has delivered the first commercial validation of its combined wet lab/in silico platform for homing in on disease-related genes in the thick of the genome, signing two collaboration agreements with GSK plc, with a potential value of $200 million per target.
Read More

Paradigm's AU$16M moves Zilosul to pivotal osteoarthritis trials

Dec. 9, 2024
By Tamra Sami
Paradigm Biopharmaceuticals Ltd. raised AU$16 million (US$10.31 million) in a placement that will allow the company to start a global phase III trial with its lead product, Zilosul (injectable pentosan polysulfate/iPPS), to treat osteoarthritis.
Read More
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