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Home » Topics » Disease categories and therapies » Inflammatory

Inflammatory
Inflammatory RSS Feed RSS

TRIM14 is a potential therapeutic target for treating inflammation-driven diseases

March 4, 2022

Sitryx Therapeutics describes nuclear factor erythroid 2-related factor 2 activators

March 3, 2022
Hands holding arrow-shaped puzzle pieces

Huadong acquires Asia rights to drugs from Kiniksa in $662M deal

March 1, 2022
By Doris Yu
Huadong Medicine Co. Ltd.’s wholly owned subsidiary Hangzhou Zhongmei Huadong Pharmaceutical Co. Ltd. has acquired Asia-Pacific rights to two drugs from Kiniksa Pharmaceuticals Ltd. in a deal worth up to $662 million. “This collaboration aims to bring Kiniksa’s therapeutics to patients in the Asia Pacific Region suffering from severe autoimmune and inflammatory diseases,” said Sanj Patel, chairman and CEO of Kiniksa. “The collaboration also provides nondilutive capital, cost-sharing, and resources for clinical trials to accelerate our drug development and commercialization efforts.”
Read More

Huadong acquires Asia rights to drugs from Kiniksa in $662M deal

Feb. 25, 2022
By Doris Yu
Huadong Medicine Co. Ltd.’s wholly owned subsidiary Hangzhou Zhongmei Huadong Pharmaceutical Co. Ltd. has acquired Asia-Pacific rights to two drugs from Kiniksa Pharmaceuticals Ltd. in a deal worth up to $662 million. “This collaboration aims to bring Kiniksa’s therapeutics to patients in the Asia Pacific Region suffering from severe autoimmune and inflammatory diseases,” said Sanj Patel, chairman and CEO of Kiniksa. “The collaboration also provides nondilutive capital, cost-sharing, and resources for clinical trials to accelerate our drug development and commercialization efforts.”
Read More

DNA methylation mediated by METTL3-METTL14 complex is largely restricted by structured RNA elements

Feb. 21, 2022

Targeting of CRYAB with 25-hydroxycholesterol induces kills senescent cells in vitro and in vivo

Feb. 21, 2022
Skin irritation on hands

Balance beam: Third Harmonic’s start value high in KIT, scores $105M series B

Feb. 16, 2022
By Randy Osborne
Third Harmonic Bio Inc. CEO Natalie Holles said the company’s $105 million in series B money will push THB-001 – a first-in-class, highly selective, oral inhibitor of wild-type KIT – “well past the first proof-of-concept study in inducible urticaria [hives].”
Read More

A Star is born as new SIRP player aims to Electra-fy rare disease

Feb. 16, 2022
By Randy Osborne
Star Therapeutics Inc. emerged from stealth mode to tell the world about its approach to drug discovery and development in rare diseases, and to spin out Electra Therapeutics Inc., the first in a projected family of companies.
Read More

Mutant SLC6A8 correctors patented by Jnana Therapeutics

Feb. 15, 2022

Challenge Bioproducts synthesizes new PTGER4 ligands

Feb. 10, 2022
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