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BioWorld - Sunday, March 29, 2026
Home » Topics » Disease categories and therapies » Musculoskeletal

Musculoskeletal
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Proof-of-concept study of ziritaxestat in diffuse cutaneous systemic sclerosis meets endpoint

Sep. 14, 2020

Rockin’ the Casma: $50M series B comes its way

Sep. 10, 2020
By Lee Landenberger
In the more than two years since Casma Therapeutics Inc. raised its series A and completed its new $50 million series B, the company has advanced its agonist program for treating muscular dystrophy and identified new targets.
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sEH inhibition decreases expression of proinflammatory cytokines and increases Tregs in a RA model

Sep. 10, 2020

4,6- and 5,7-disubstituted isoquinolines inhibiting PKCz show promise for rheumatoid arthritis

Sep. 10, 2020

Argenx begins first-in-human study of ARGX-117

Sep. 9, 2020

Agrin-culture grows cartilage

Sep. 9, 2020

Lilly begins phase II study of LY-3471851 for SLE

Aug. 28, 2020

UCB studies dapirolizumab pegol in phase III for moderate to severely active SLE

Aug. 28, 2020

Canwell Biotech identifies new TLR7/8 agonists

Aug. 26, 2020
Rare disease illustration

Ipsen back on track with palovarotene in FOP

Aug. 25, 2020
By Cormac Sheridan
DUBLIN – Ipsen SA is on track for an NDA filing for palovarotene in fibrodysplasia ossificans progressiva (FOP), an ultra-rare disease characterized by the gradual replacement of skeletal muscle and connective tissue with bone, following an interim analysis of phase III data which indicates that the drug may have a substantial effect on the disease process.
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