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BioWorld - Sunday, April 26, 2026
Home » Topics » Disease categories and therapies » Neurology/psychiatric

Neurology/psychiatric
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3D illustration of a nerve cell
Neurology/Psychiatric

Bsense Bio nominates dual Kv7.2/3 and TRPV1 ion channel modulator as clinical candidate for chronic pain

Dec. 7, 2023
Bsense Bio Therapeutics Ltd. has nominated BSEN-760, a dual Kv7.2/3 and TRPV1 ion channel modulator, as a clinical candidate for the treatment of chronic pain.
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Neurology/Psychiatric

TRV-045 demonstrates efficacy for both reversal and prevention of CIPN in mice

Dec. 7, 2023
At the recent American College of Neuropsychopharmacology meeting, Trevena Inc. presented preclinical data for the novel selective sphingosine 1-phosphate S1P1 receptor modulator TRV-045, being developed for the treatment of chemotherapy-induced peripheral neuropathy (CIPN).
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China’s NMPA greenlights Jingxin’s dimdazenil for insomnia

Dec. 6, 2023
By Tamra Sami
China’s National Medical Products Administration (NMPA) approved Zhejiang Jingxin Pharmaceutical Co. Ltd.’s dimdazenil (EVT-201) for short-term treatment of insomnia. Jingxin filed the NDA in China in April 2022.
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Neurostar TMS nets expanded approval in Japan

Dec. 6, 2023
By Marian (YoonJee) Chu
Neuronetics Inc. gained expanded approval in Japan for its transcranial magnetic stimulation (TMS) system to treat major depressive disorder called the Neurostar TMS, helping the Malvern, Pa.-based company increase its footprint in Asia.
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Neurons

Upbeat phase IIb data from Paradigm shift Neurosense focus to pivotal bid

Dec. 5, 2023
By Randy Osborne
Neurosense Therapeutics Ltd. failed to impress Wall Street with top-line data from its phase IIb study called Paradigm with PrimeC, a fixed-dose combination of ciprofloxacin and celecoxib, in amyotrophic lateral sclerosis.
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Myelinated axons in a rat spinal root.
Neurology/Psychiatric

Rev-erbA-α agonist ameliorates multiple sclerosis in mice

Dec. 5, 2023
Nuclear receptor subfamily 1 group D member (NR1D1), also known as Rev-erbA-α, is highly expressed in the liver, adipose tissue, brain and skeletal muscle.
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Woman sleeping
Neurology/Psychiatric

NLS Pharmaceutics enters option agreement with Aexon Labs for dual orexin receptor agonist platform

Dec. 5, 2023
NLS Pharmaceutics Ltd. has entered into an exclusive worldwide option agreement with Aexon Labs Inc.
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Neurology/Psychiatric

Longboard’s 5-HT2C superagonist yields positive results in preclinical models of epilepsy

Dec. 5, 2023
Serotonin 5-HT2 receptor agonists have shown efficacy in treating seizure disorders, such as epilepsy. At the American Epilepsy Society meeting this week, Longboard Pharmaceuticals Inc. presented data on their 5-HT2C receptor superagonist LP-352 for the treatment of epilepsy.
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Brain as light bulb filament
Neurology/Psychiatric

Oryzon Genomics awarded grant to support preclinical development of ORY-4001 in ALS

Dec. 5, 2023
Oryzon Genomics SA has been awarded a $498,690 grant by the ALS Association to support the regulatory preclinical development of ORY-4001, a highly selective histone deacetylase 6 (HDAC6) inhibitor, for amyotrophic lateral sclerosis (ALS).
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An illustration of the connections between muscle fibers and a motor neuron.
Neurology/Psychiatric

Stathmin-2 is new player in the ALS gene-verse

Dec. 5, 2023
By Subhasree Nag
A multi-institutional research team has suggested that aberrant TDP-43 processing of the pre-mRNA of a microtubule-associated protein, stathmin-2 (STMN2), may be the primary contributor to amyotrophic lateral sclerosis (ALS).
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