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BioWorld - Monday, December 29, 2025
Home » Topics » Disease categories and therapies » Neurology/psychiatric

Neurology/psychiatric
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Neurology/psychiatric

Suven Life Sciences divulges new muscarinic M4 receptor PAMs

May 9, 2025
Suven Life Sciences Ltd. has synthesized muscarinic M4 receptor positive allosteric modulators (PAMs) reported to be useful for the treatment of pain, psychiatric disorders and neurological disorders.
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Brain maze
Neurology/psychiatric

Researchers uncover CFTR as a potential therapeutic target for ADHD

May 9, 2025
No Comments
Individuals with cystic fibrosis show a notably higher rate of attention deficit hyperactivity disorder (ADHD) symptoms than the general population. This association points to a possible role of the cystic fibrosis transmembrane conductance regulator (CFTR) gene, whose mutations cause cystic fibrosis, in the development of ADHD.
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3D illustration of a liposome
Neurology/psychiatric

Ahead Therapeutics advances myasthenia gravis program toward toxicology studies

May 9, 2025
No Comments
Ahead Therapeutics SL has received positive feedback from the EMA on its way toward initiating regulatory toxicology studies for its lead program in myasthenia gravis. The feedback supports the company’s scientific approach.
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Precision Neuro eletrode array

Precision Neuro leads BCI race following FDA clearance

May 8, 2025
By Shani Alexander
The recent 510(k) clearance by the U.S. FDA for a core part of Precision Neuroscience Corp. brain-computer interface technology is certainly a boon for the company, and others developing the devices. For the millions of people suffering from health disorders, such as motor neuron disease, spinal cord injury or severe stroke, its sign that a solution which could transform their lives could be just a few years away.
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Neurology/psychiatric

Tenvie Therapeutics discovers new TMEM175 modulators

May 8, 2025
Tenvie Therapeutics Inc. has described endosomal/lysosomal proton channel TMEM175 modulators reported to be useful for the treatment of cancer, neurological disorders, lysosomal storage disorders and inflammatory disorders.
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Cross-section of brain
Neurology/psychiatric

Blocking GAPDH aggregation to mitigate stroke injury

May 8, 2025
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Stroke accounts for nearly 12% of all deaths worldwide, making it the second leading cause of death. In acute ischemic stroke, the ischemia and subsequent return of blood flow create oxidative and nitrosative stress that can overwhelm neurons and disable important circuitry.
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Illustration of muscle tissue anatomy
Neurology/psychiatric

Solve FSHD supports Armatus Bio drug for facioscapulohumeral muscular dystrophy

May 7, 2025
No Comments
Armatus Bio Inc.’s development of ARM-201, an AAV-delivered microRNA therapy for facioscapulohumeral muscular dystrophy (FSHD), has been boosted by a $3 million investment by Solve FSHD.
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FDA clears Satsuma’s Atzumi for migraine

May 6, 2025
By Karen Carey
Following a complete response letter last year, Satsuma Pharmaceuticals Inc. received U.S. FDA approval of dihydroergotamine nasal powder to treat acute migraine with or without aura. Branded Atzumi, it is the first product that uses Satsuma’s SMART (Simple MucoAdhesive Release Technology) platform that combines an advanced powder and device technology aimed at making delivery more simple.
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Neurology/psychiatric

New lipid prodrugs of bromolysergide disclosed in Seaport Therapeutics patent

May 6, 2025
Seaport Therapeutics Inc. has divulged lipid prodrugs of bromolysergide reported to be useful for the treatment of cluster headache and mood disorder.
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Conceptual 3D illustration showing degradation of motor neuron
Neurology/psychiatric

Alchemab and Lilly sign licensing agreement for ATLX-1282

May 6, 2025
No Comments
Alchemab Therapeutics Ltd. has entered into a licensing agreement with Eli Lilly and Co. for ATLX-1282, Alchemab’s first-in-class IND-ready program targeting a novel receptor and mechanism for amyotrophic lateral sclerosis (ALS) and other neurodegenerative conditions.
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