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BioWorld - Saturday, April 11, 2026
Home » Topics » Disease categories and therapies » Ocular

Ocular
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Tarsus beefs up blepharitis drug launch on back of $100M offering

March 1, 2024
By Caroline Richards
With its sights set on expanding the commercial launch of Xdemvy (lotilaner ophthalmic solution, 0.25%) to treat Demodex blepharitis in the U.S., Tarsus Pharmaceuticals Inc. has priced an underwritten public offering of common stock, selling 2.8 million shares for $32 each, taking the expected gross proceeds to about $100 million.
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Green strand of DNA

Pulsesight advancing eye therapies delivered via electroporation

Feb. 29, 2024
By Nuala Moran
Ocular gene therapy specialist Pulsesight Therapeutics SAS has launched with seed funding and is raising a series A to take forward two programs using electroporation to deliver plasmid DNA in the treatment of wet age-related macular degeneration and geographic atrophy.
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Green strand of DNA

Pulsesight advancing eye therapies delivered via electroporation

Feb. 28, 2024
By Nuala Moran
Ocular gene therapy specialist Pulsesight Therapeutics SAS has launched with seed funding and is raising a series A to take forward two programs using electroporation to deliver plasmid DNA in the treatment of wet age-related macular degeneration and geographic atrophy.
Read More
Eye and financial charts

Palatin to tweak second PL-9643 phase III in dry eye disease

Feb. 28, 2024
By Randy Osborne
After trading as low as $2.04, shares of Palatin Technologies Inc. (NYSE:PTN) closed Feb. 28 down $1.57, or 39.7%, ending at $2.39 on word of results from the phase III pivotal Melody-1 trial with melanocortin pan-agonist PL-9643 vs. vehicle in dry eye disease.
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Eye, DNA double helix illustration.
Ocular

Pulsesight Therapeutics launches to develop non-viral gene therapies for retinal diseases

Feb. 28, 2024
Pulsesight Therapeutics SAS has launched with seed financing, with the aim of developing disruptive non-viral gene therapies with minimally invasive delivery technology.
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Ocular

Rezolute reports new KLKB1 inhibitors

Feb. 21, 2024
Rezolute Inc. has patented new plasma kallikrein (KLKB1) inhibitors reported to be useful for the treatment of diabetic macular edema, diabetic retinopathy and uveitis.
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Eye illustration

Innovent thyroid eye therapy hits phase III goal, spurs China NDA

Feb. 20, 2024
By Marian (YoonJee) Chu
In a crowded thyroid eye disease (TED) space, Innovent Biologics Inc. reported positive late-stage findings for its TED therapy, IBI-311, spurring the Suzhou, China-based biopharma to file for regulatory approval in China.
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A fundus image of a healthy retina.
Ocular

Novel inducible mouse model of North Carolina macular dystrophy

Feb. 20, 2024
At the recent Macula Society Meeting, researchers from the Molecular Insight Research Foundation reported on the creation of a novel murine model of North Carolina macular dystrophy.
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Ocular

Novel CA II inhibitor shows significant IOP-reducing properties in vivo

Feb. 16, 2024
Investigators from Tanta University and affiliated organizations have reported the discovery and preclinical characterization of novel carbonic anhydrase (CA) isoform II inhibitors as potential antiglaucoma agents.
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Masayo Takahashi, CEO, Vision Care
Ocular

Newco news: Vision Care’s iPS retinal cells primed for global market

Feb. 13, 2024
By Tamra Sami
Vision Care Group CEO Masayo Takahashi led the world's first clinical study of a retinal cell transplant derived from induced pluripotent stem cells (iPS cells) in 2014 when she led the Laboratory for Retinal Regeneration at Japan’s Riken Center for Biosystems Dynamics Research. In 2019, she founded Vision Care and subsequently founded two subsidiary companies dedicated to developing cell and gene therapies.
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