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BioWorld - Saturday, May 16, 2026
Home » Topics » Disease categories and therapies » Respiratory

Respiratory
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Photo of hands holding a baby
Respiratory

HCW Biologics’ HCW11-040 prevents bronchopulmonary dysplasia

May 15, 2026
No Comments
HCW Biologics Inc.’s HCW11-040 has been shown in IND-enabling studies to prevent bronchopulmonary dysplasia (BPD), a rare pediatric disease affecting underweight premature infants.
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Illustration of alveoli and lungs
Respiratory

Novel PROTAC degrader targeting SAMHD1 disclosed

May 13, 2026
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Chinese researchers reported the discovery and preclinical characterization of a novel PROTAC degrader designed to target SAMHD1 and intended for the treatment of pulmonary fibrosis.
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Hantavirus cells

APAC monitors hantavirus as Singapore isolates 2 from cruise ship

May 12, 2026
By Marian (YoonJee) Chu
No Comments
Singapore’s Communicable Diseases Agency on May 7 said that it isolated two residents for hantavirus testing after the individuals disembarked from an Atlantic cruise ship on May 2 and May 6, respectively. The measure comes in response to the cluster of cases from the cruise ship, MV Hondius, that has resulted in three deaths so far.
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Hantavirus cells

APAC monitors hantavirus as Singapore isolates 2 from cruise ship

May 8, 2026
By Marian (YoonJee) Chu
No Comments
Singapore’s Communicable Diseases Agency on May 7 said that it isolated two residents for hantavirus testing after the individuals disembarked from an Atlantic cruise ship on May 2 and May 6, respectively. The measure comes in response to the cluster of cases from the cruise ship, MV Hondius, that has resulted in three deaths so far.
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Rendering of a key measles protein targeted by neutralizing human antibodies
Infection

First measles treatment advances as vaccination rates drop

May 7, 2026
By Mar de Miguel
No Comments
Scientists at the La Jolla Institute for Immunology have identified and characterized human antibodies that neutralize the measles virus by blocking its entry into the cell. This is the first time that antibodies have been shown to bind effectively to two essential viral proteins, creating a dual blockade that prevents infection. Unlike the current vaccine, which is based on an attenuated virus and is not recommended for immunocompromised individuals, these monoclonal antibodies could be used both as a new vaccine approach and as a treatment for the entire population.
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Respiratory

Agomab Therapeutics patents new TGFBR1 inhibitors

May 5, 2026
Agomab Therapeutics NV has identified new TGF-β receptor type-1 (TGFBR1; ALK5; SKR4; TβR-I) inhibitors designed for use in the treatment of idiopathic pulmonary fibrosis.
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Going public ticker

Mists of Avalyn thicken with $300M IPO for inhaled drugs

April 30, 2026
By Randy Osborne
No Comments
The memory of Merck & Co. Inc.’s $10 billion takeover last year of inhaled respiratory drug specialist Verona Pharma plc may not have been far from the minds of Wall Street speculators as Avalyn Pharma Inc. priced its IPO, selling about 16.6 million shares at the high end of the targeted range, or $18 each, to reap about $300 million. The stock (NASDAQ:AVLN) came out of the gate strong on the first day of trading and closed April 30 at $29.49, up $11.49, or 64%.
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Lungs anatomy
Respiratory

Addex’s GABA-B PAM studied in IPF-related chronic cough model

April 29, 2026
No Comments

Addex Therapeutics Ltd. has released preclinical data demonstrating antitussive activity of its γ-aminobutyric acid subtype B receptor (GABA-B) positive allosteric modulator (PAM) candidate in a bleomycin-induced idiopathic pulmonary fibrosis (IPF)-exacerbated chronic cough model.


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Three red darts on target

Sun Pharma to acquire Merck spinoff Organon for $11.75B

April 28, 2026
By Marian (YoonJee) Chu
No Comments
Sun Pharmaceuticals Industries Ltd. will pay $11.75 billion cash to acquire Organon & Co. The transaction is expected to close in early 2027. The addition of Organon’s women’s health products, legacy drug brands and biosimilars are expected to boost Mumbai, India-based Sun’s global reach. The all-cash buy is also expected to relieve Jersey City, N.J.-based Organon of an $8.6 billion debt pile, accumulated after its debt-laden 2021 spinout from Merck & Co. Inc.
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Three red darts on target

Sun Pharma to acquire Merck spinoff Organon for $11.75B

April 27, 2026
By Marian (YoonJee) Chu
No Comments
Sun Pharmaceuticals Industries Ltd. will pay $11.75 billion cash to acquire Organon & Co. The transaction is expected to close in early 2027. The addition of Organon’s women’s health products, legacy drug brands and biosimilars are expected to boost Mumbai, India-based Sun’s global reach. The all-cash buy is also expected to relieve Jersey City, N.J.-based Organon of an $8.6 billion debt pile, accumulated after its debt-laden 2021 spinout from Merck & Co. Inc.
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