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BioWorld - Thursday, February 12, 2026
Home » Topics » Disease categories and therapies » Respiratory

Respiratory
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Illustration of Zephyr valve deployment in lung

After scrapped IPO, Pulmonx raises $66M to back minimally invasive emphysema valve

May 5, 2020
By Stacy Lawrence
Chronic obstructive pulmonary disease (COPD) is one of the most dangerous comorbidities for COVID-19 patients – as well as a major cause of death that predates the current pandemic. Pulmonx Corp. has the first minimally invasive valve to treat severe emphysema, which is a form of COPD that accounts for about one-quarter of the patients.
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Phase III data for HL-301 in acute bronchitis

May 5, 2020

Mesoblast initiates phase II/III study of remestemcel-L in patients with COVID-19 ARDS

May 4, 2020
1QBit-xrAI-Chest-X-ray-Abnormal.png

Health Canada accelerates approval of AI-driven COVID-19 tool

April 30, 2020
By David Godkin
TORONTO – Within a week of completing clinical trials the chest radiography AI tool developed by Vancouver, B.C.-based 1Qbit Inc. has been given the all-clear from Health Canada for deployment across the country. The XrAI was originally developed to better identify patients with respiratory illness including SARS, pneumonia and tuberculosis (TB), but then in February was tested on a publicly available data set of COVID-19 X-ray images.
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Chimerix initiates phase II/III study of DSTAT in patients with severe COVID-19

April 30, 2020

KCNMB1 methylation increases BK channel activity, resulting in myofibroblast differentiation in IPF

April 29, 2020
Lungpacer-DPTS-device.png

Lungpacer wins EUA for device to wean patients off ventilators

April 28, 2020
By Meg Bryant
Reports of unusually high death rates for COVID-19 patients on ventilators have raised alarms, and some doctors are looking to reduce reliance on the breathing machines when possible. To advance that goal, Lungpacer Medical Inc., of Vancouver, British Columbia, has obtained an emergency use authorization (EUA) from the U.S. FDA for its Lungpacer diaphragmatic pacing therapy system (DPTS) for immediate use in ventilator patients at high risk of weaning failure, including patients with the novel coronavirus.
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Pliant Therapeutics discovers integrin alphavbeta1 and/or alphavbeta6 antagonists

April 28, 2020

Building on previous AAV deals, Vertex partners with Affinia in a $1.6B agreement

April 27, 2020
By Lee Landenberger
Weeks after raising an oversubscribed $60 million series A, Affinia Therapeutics Inc., of Waltham, Mass., is collaborating with Vertex Pharmaceuticals Inc. in a far larger deal, one potentially worth more than $1.6 billion.
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Promising data for COVID-19 patients with ARDS treated with remestemcel-L

April 27, 2020
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