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BioWorld - Saturday, December 20, 2025
Home » Topics » Disease categories and therapies » Respiratory

Respiratory
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Asia cityscape, map with Thailand under magnifier

Lotus acquires Teva Thailand to build Southeast Asian footprint

June 11, 2024
By Tamra Sami
Lotus Pharmaceutical Co. Ltd. is acquiring the Thailand business and commercial entity of Teva Pharma Thailand to expand its footprint in Southeast Asia.
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Asia cityscape, map with Thailand under magnifier

Lotus acquires Teva Thailand to build Southeast Asian footprint

June 10, 2024
By Tamra Sami
Lotus Pharmaceutical Co. Ltd. is acquiring the Thailand business and commercial entity of Teva Pharma Thailand to expand its footprint in Southeast Asia.
Read More
deep breath ultrasound
Patents

Deep Breathe’s wearable AI-powered POC lung ultrasound imaging system

June 7, 2024
By Simon Kerton
London, Ontario-based Deep Breathe Inc. filed for protection of a wearable ultrasound sensor that is used to obtain ultrasound data, and digital ultrasound images are processed using a machine learning model to predict the probability of lung sliding and detection of pneumothorax (collapsed lung) if lung sliding is absent or deem it likely if lung sliding is present.
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AI-generated image of person in hazmat suit in poultry farm with chickens out of focus in the background
Infection

Preclinical H5 mRNA vaccine immunizes and prevents mortality

June 7, 2024
A preclinical trial in mice and ferrets of an experimental mRNA vaccine against the H5 highly pathogenic avian influenza (HPAI) virus generated neutralizing antibodies and prevented severe illness and mortality of the animals.
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sleep apena app
Patents

Researchers develop app to improve sleep apnea treatment adherence

June 6, 2024
By Simon Kerton
Researchers from the University of Chicago and Northwestern University have filed for protection of an mobile application to track individualized patient needs, engagement in continuous positive airway pressure machine use, and the correlation of risk behaviors to determine sleep apnea treatment progress.
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Respiratory

S1PR3 is target in acute respiratory distress syndrome

June 6, 2024
Excessive inflammatory response and endothelial barrier dysfunction are the two major pathophysiological changes in acute respiratory distress syndrome (ARDS). Sphingosine-1-phosphate S1P3 receptor (S1PR3) is a G protein-coupled receptor involved in the regulation of inflammation and vascular barrier function in some diseases, but its function in ARDS is not fully understood.
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Respiratory

New TGF-β receptor type-1 inhibitors revealed in Chiesi patent

June 5, 2024
Chiesi Farmaceutici SpA has divulged TGF-β receptor type-1 (TGFBR1; ALK5; SKR4; TβR-I) inhibitors reported to be useful for the treatment of idiopathic pulmonary fibrosis.
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Acquisition puzzle

Edwards forgoes critical care spin, sells unit to BD for $4.2B

June 3, 2024
By Holland Johnson
Edwards Lifesciences Corp. is selling its critical care product group to Becton Dickison and Co. (BD) for $4.2 billion in cash, forgoing its previously announced plans to spin off the unit into a separate business. The transaction is expected to close before the end of the calendar year.
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Digital lungs illustration
Respiratory

PARP inhibition results in significant resolution of pulmonary fibrosis in sheep

June 3, 2024
Researchers from Federation University Australia and affiliated organizations have reported data from a study that aimed to assess the therapeutic efficacy of the poly (ADP-ribose) polymerase (PARP) inhibitor olaparib in a large animal model of pulmonary fibrosis.
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Biomarkers

CROCCP2 gene behind COPD pathogenesis, study unveils

May 30, 2024
Alternative splicing is known to play an important role in tissue development. Scientists at Brigham and Women’s Hospital have looked into the association between a chronic obstructive pulmonary disease (COPD) genetic variant and cell-specific splicing of putative ciliary rootlet coiled-coil protein-like 1 protein (CROCCP2).
Read More
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