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Home » Topics » Disease categories and therapies » Respiratory

Respiratory
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Respiratory

Tibet Haisco Pharmaceutical identifies phosphodiesterase PDE4B inhibitors

March 5, 2024
A Tibet Haisco Pharmaceutical Co. Ltd. patent describes new phosphodiesterase PDE4B inhibitors potentially useful for the treatment of cancer, chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis.
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Liver
Endocrine/Metabolic

Max Biopharma and Metaba study effects of oxysterol drug candidates on metabolic processes

Feb. 27, 2024
Max Biopharma Inc. and Metaba LLC are collaborating to study the effects of oxysterol drug candidates that target metabolic dysfunction-associated steatohepatitis (MASH, formerly nonalcoholic steatohepatitis or NASH), idiopathic pulmonary fibrosis, chronic inflammation, and atherosclerosis on metabolic processes.
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Scanning electron micrograph of human RSV virions
Infection

RSV infection model could shed light on viral transmission and pathogenesis

Feb. 22, 2024

Researchers from the Peking University Health Science Center have developed a murine model of RSV infection based on the knockout of the Rag2 gene using CRISPR/Cas9 (Rag2-/- mice).


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Respiratory

Humanwell Healthcare identifies new LPAR1 antagonists

Feb. 21, 2024
Humanwell Healthcare (Group) Co. Ltd. has disclosed triazole compounds acting as lysophosphatidic acid receptor 1 (LPAR1; EDG2) antagonists.
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Stock table, gold arrow pointing down

Rapt slapped with phase II hold on CCR4 prospect

Feb. 20, 2024
By Randy Osborne
On the verge of top-line data from its phase IIb trial with oral small-molecule CC chemokine receptor 4 (CCR4) antagonist zelnecirnon in atopic dermatitis (AD), due around the middle of this year, Rapt Therapeutics Inc. said the U.S. FDA has imposed a clinical hold on that study with the otherwise promising drug, also known as RPT-193, in AD as well as the phase IIa trial with the same compound in asthma.
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Respiratory

Chiesi Farmaceutici patent describes DDR1 and DDR2 inhibitors for IPF

Feb. 20, 2024
Chiesi Farmaceutici SpA has detailed new discoidin domain-containing receptor DDR1 and DDR2 inhibitors reported to be useful for the treatment of idiopathic pulmonary fibrosis (IPF).
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Gene editing illustration
Respiratory

Intellia and Recode collaborate on genomic medicines for cystic fibrosis

Feb. 16, 2024
Intellia Therapeutics Inc. and Recode Therapeutics Inc. have established a strategic collaboration to develop novel genomic medicines for the treatment of cystic fibrosis.
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Respiratory

New DPP4 inhibitors for lung disease disclosed in Scripps Research Institute patent

Feb. 14, 2024
Scripps Research Institute has synthesized dipeptidyl peptidase 4 inhibitors reported to be useful for the treatment of lung diseases.
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Scientist, microscope and dropper
Dermatologic

Attovia Therapeutics to use financing to advance Attobody pipeline

Feb. 9, 2024
Attovia Therapeutics Inc. has announced the closing of the $30 million second tranche of its $60 million series A financing.
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Digital lungs illustration
Respiratory

Anima Biotech’s IPF candidate disrupts transformation of fibroblasts into fully differentiated myofibroblasts

Feb. 8, 2024
Anima Biotech Inc. has released promising preclinical data on its new candidate, which has potential for treating idiopathic pulmonary fibrosis (IPF).
Read More
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