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BioWorld - Saturday, December 13, 2025
Home » Topics » Drugs » Antibody

Antibody
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Antibodies (light blue) and G protein-coupled receptors (purple)
Newco news

Alkira Bio exits stealth via seed round to develop GPCR-targeting antibodies

July 30, 2024
By Tamra Sami
Alkira Bio, a new spinout from Australia’s Florey Institute of Neuroscience and Mental Health has emerged from stealth mode thanks to seed funding from Curie.bio. Although the amount of funding is not disclosed, Curie.bio typically invests $5 million to $10 million in a founder company and then co-pilots the drug discovery program, deploying drug development experts to its portfolio companies to help navigate decision making as part of the deal, Florey researcher turned Alkira Bio CEO Daniel Scott told BioWorld.
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Monoclonal antibody illustration

European Commission approves Cstone PD-L1 sugemalimab in NSCLC

July 30, 2024
By Tamra Sami
The European Commission has approved Cstone Pharmaceuticals Ltd.’s PD-L1 monoclonal antibody, sugemalimab, in combination with platinum-based chemotherapy for first-line treatment of adults with metastatic non-small-cell lung cancer with no sensitizing EGFR mutations, or ALK, ROS1 or RET genomic tumor aberrations.
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Antibodies (light blue) and G protein-coupled receptors (purple)
Neurology/psychiatric

Alkira Bio exits stealth via seed round to develop GPCR-targeting antibodies

July 30, 2024
By Tamra Sami
Alkira Bio, a new spinout from Australia’s Florey Institute of Neuroscience and Mental Health has emerged from stealth mode thanks to seed funding from Curie.bio. Although the amount of funding is not disclosed, Curie.bio typically invests $5 million to $10 million in a founder company and then co-pilots the drug discovery program, deploying drug development experts to its portfolio companies to help navigate decision making as part of the deal, Florey researcher turned Alkira Bio CEO Daniel Scott told BioWorld.
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Cancer

FDA clears IND for COM-503

July 30, 2024
The US FDA has cleared an IND application for COM-503, high affinity anti-IL-18 binding protein antibody, in solid tumors.
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Tinted Euro symbol

Confo's €60M series B targets GPCR, endocrine/metabolic disorders

July 26, 2024
By Nuala Moran
GPCR drug discovery and development specialist Confo Therapeutics NV has closed a €60 million (US$65.2 million) series B round that will fund a significant expansion of the inhouse portfolio while it continues to turn the handle on its technology platform to generate more compounds for partnering.
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Dr. Widjaja viewing experimental data on the computer
Aging

Stop interleukin-11 to age better and live longer

July 26, 2024
By Mar de Miguel
Increased life expectancy also comes with age-related diseases. But what causes one to age? Although there is no single answer, scientists at Duke-National University of Singapore have shown in mice that interleukin-11 (IL-11) promoted aging. Blocking it improved health and lifespan.
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Sickle cell illustration
Hematologic

Actinium Pharmaceuticals obtains FDA clearance for trial of Iomab-ACT in sickle cell disease

July 26, 2024
Actinium Pharmaceuticals Inc. has received FDA clearance of an IND application to study Iomab-ACT for targeted conditioning prior to a bone marrow transplant (BMT) in patients with sickle cell disease. 
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Antibodies (light blue) and G protein-coupled receptors (purple)
Newco news

Alkira Bio exits stealth via seed round to develop GPCR-targeting antibodies

July 25, 2024
By Tamra Sami
Alkira Bio, a new spinout from Australia’s Florey Institute of Neuroscience and Mental Health has emerged from stealth mode thanks to seed funding from Curie.bio. Although the amount of funding is not disclosed, Curie.bio typically invests $5 million to $10 million in a founder company and then co-pilots the drug discovery program, deploying drug development experts to its portfolio companies to help navigate decision making as part of the deal, Florey researcher turned Alkira Bio CEO Daniel Scott told BioWorld.
Read More

ODAC: FDA treatment phase trial requirement costly but needed

July 25, 2024
By Mari Serebrov
Even as U.S. lawmakers continue to push back against the rising price of prescription drugs and patients with life-threatening diseases clamor for access to new treatments, the FDA is considering a step that could increase the cost and lengthen the development time of therapies targeting non-small-cell lung cancer and perhaps other solid tumors.
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Novartis campus in Basel, Switzerland

With Dren deal, Novartis has three of year’s top collaborations

July 24, 2024
By Lee Landenberger
A new collaboration with Dren Bio Inc. means Novartis Pharma AG has negotiated two of the biggest deals of 2024, with its parent company Novartis AG signing a third. Privately held Dren is getting $150 million up front and the chance to ultimately bring in $2.85 billion. The $150 million up-front payment includes a $25 million equity investment.
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