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BioWorld - Thursday, April 16, 2026
Home » Topics » Drugs » Antibody-drug conjugate

Antibody-drug conjugate
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Immuno-oncology

Amanitin-based antibody-drug conjugate tested in pancreatic cancer

Jan. 15, 2025
A recent study has introduced a novel class of antibody-drug conjugates (ADCs) targeting trophoblast cell surface antigen 2 (TROP2), a protein overexpressed in pancreatic ductal adenocarcinoma (PDAC), one of the deadliest forms of cancer.
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Wuxi Bio licenses trispecific T-cell engager to Candid for $925M

Jan. 14, 2025
By Tamra Sami
Wuxi Biologics Co. Ltd. is licensing a preclinical trispecific T-cell engager to Candid Therapeutics Inc. in a deal worth up to $925 million plus royalties.
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AI-generated image for cancer cells observed under a microscope
Immuno-oncology

CSPC’s SYS-6041 cleared to enter clinic in China

Jan. 13, 2025
CSPC Pharmaceutical Group Ltd. has obtained clinical trial approval from China’s National Medical Products Administration (NMPA) for SYS-6041, an antibody-drug conjugate, for advanced solid tumors.
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Gold wireframe handshake
Immuno-oncology

Zai Lab partners with Medilink on LRRC15 antibody-drug conjugate for solid tumors

Jan. 10, 2025
Zai Lab Ltd. has entered into a new strategic collaboration and worldwide license agreement with Medilink Therapeutics (Suzhou) Co. Ltd. to use Medilink’s TMALIN antibody-drug conjugate (ADC) platform.
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Lab glassware and antibodies art concept
Immuno-oncology

Sotio licenses fully human antibodies from Biocytogen to support SOT-109 development

Jan. 10, 2025
Sotio Biotech AS has announced the licensing of fully human antibodies from Biocytogen Pharmaceuticals (Beijing) Co. Ltd.
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Wuxi Bio licenses trispecific T-cell engager to Candid for $925M

Jan. 8, 2025
By Tamra Sami
Wuxi Biologics Co. Ltd. is licensing a preclinical trispecific T-cell engager to Candid Therapeutics Inc. in a deal worth up to $925 million plus royalties.
Read More
Antibody-drug conjugate illustration

Araris signs $780M deal with Chugai for multi-warhead ADCs

Jan. 8, 2025
By Nuala Moran
The wheels of the antibody-drug conjugate (ADC) juggernaut keep on turning, with Araris Biotech AG announcing a deal with a headline value of $780 million to apply its multi-payload linker technology to generate novel ADCs for Chugai Pharmaceutical Co. Ltd.
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Immuno-oncology

SYS-6045 cleared for clinic in China for advanced solid tumors

Jan. 8, 2025
CSPC Pharmaceutical Group Ltd.’s antibody-drug conjugate SYS-6045 has been granted clearance by China’s National Medical Products Administration (NMPA) to enter clinical trials.
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Immuno-oncology

Avenzo licenses ex-China rights to Duality’s EGFR/HER3 bispecific ADC

Jan. 8, 2025
Avenzo Therapeutics Inc. and Duality Biotherapeutics (Suzhou) Co. Ltd. have entered into an exclusive license agreement.
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Deal handshake with coin, chart background

New year, new $1B deal: Roche taps Innovent for new DLL3 ADC drug

Jan. 7, 2025
By Marian (YoonJee) Chu
Roche Holding AG kicked off the new year (again) with a potential $1 billion deal, including $80 million up front, for exclusive rights to Innovent Biologics Inc.’s IBI-3009, a DLL3-targeting antibody-drug conjugate (ADC) candidate that recently entered a phase I study.
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