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BioWorld - Sunday, January 18, 2026
Home » Topics » Drugs » Bispecific antibody

Bispecific antibody
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Abbvie snags PD-1/VEGF bispecific in potential $5B Remegen deal

Jan. 13, 2026
By Jennifer Boggs
No Comments
With rumors regarding a couple of potential mega-mergers making the rounds, the week of the annual J.P. Morgan Healthcare Conference kicked off with the official disclosure of some billion-dollar collaborations, leading with Abbvie Inc.’s exclusive licensing deal with Remegen Co. Ltd. for PD-1/VEGF-targeted bispecific antibody RC-148.
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Black and white arrows merging on blue background

Abbvie snags PD-1/VEGF bispecific in potential $5B Remegen deal

Jan. 13, 2026
By Jennifer Boggs
No Comments
With rumors regarding a couple of potential mega-mergers making the rounds, the week of the annual J.P. Morgan Healthcare Conference kicked off with the official disclosure of some billion-dollar collaborations, leading with Abbvie Inc.’s exclusive licensing deal with Remegen Co. Ltd. for PD-1/VEGF-targeted bispecific antibody RC-148.
Read More
Close up of man's eye

Going Ollin on AMD, DME: Vabysmo in phase Ib crosshairs

Jan. 9, 2026
By Randy Osborne
No Comments
Ollin Biosciences Inc. is gearing up for global phase III trials this year after disclosing favorable top-line results from its randomized, head-to-head phase Ib Jade study comparing OLN-324, a next-generation VEGF/Ang2 bispecific antibody, to Vabysmo (faricimab, Roche AG), which takes aim at the same targets. The drugs were tested in more than 160 patients with diabetic macular edema (DME) or wet age-related macular degeneration (AMD).
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Drug discovery illustration
Immune

AI drug discovery brings $2B+ Sanofi deal to 1-year-old Earendil

Jan. 7, 2026
By Karen Carey
No Comments
Securing a second major partnership with Sanofi SA – this time worth a potential $2.56 billion – Earendil Labs will provide its AI-driven discovery platform to find new therapeutics for autoimmune and inflammatory diseases.
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AI drug discovery brings $2B+ Sanofi deal to 1-year-old Earendil

Jan. 6, 2026
By Karen Carey
No Comments
Securing a second major partnership with Sanofi SA – this time worth a potential $2.56 billion – Earendil Labs will provide its AI-driven discovery platform to find new therapeutics for autoimmune and inflammatory diseases.
Read More

AI drug discovery brings $2B+ Sanofi deal to 1-year-old Earendil

Jan. 5, 2026
By Karen Carey
No Comments
Securing a second major partnership with Sanofi SA – this time worth a potential $2.56 billion – Earendil Labs will provide its AI-driven discovery platform to find new therapeutics for autoimmune and inflammatory diseases.
Read More
Illustration of cancer cell in crosshairs being destroyed
Immuno-oncology

Three Helius solid tumor candidates gain clinical trial clearance

Dec. 31, 2025
No Comments
Shanghai Henlius Biotech Inc. has announced acceptance of IND applications by China’s National Medical Products Administration (NMPA) for three differentiated candidates for the treatment of solid tumors.
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Hand pointing to IPOs on line graph

Hanx Bio sees stock drop 46% in $75M Hong Kong IPO debut

Dec. 30, 2025
By Tamra Sami
No Comments
Hanx Biopharmaceuticals (Wuhan) Co., Ltd. raised HK$586 million (US$75.37 million) in its IPO on the Hong Kong Securities Exchange (HKEX:3378) on Dec. 23 to advance its clinical stage immuno-oncology pipeline.
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Skin irritation on hands

J&J’s phase IIb AD bispecific washes up on Jersey shore

Dec. 29, 2025
By Randy Osborne
No Comments
The strategy of taking aim at IL-4Ra (type I and II receptors) and IL-31 by way of a bispecific antibody in atopic dermatitis (AD) has not worked out as well as Johnson & Johnson (J&J) hoped when, last May, the firm paid $1.25 billion to bring the product aboard by acquiring Yellow Jersey Therapeutics, a wholly owned subsidiary of Numab Therapeutics AG.
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Hand pointing to IPOs on line graph

Hanx Bio sees stock drop 46% in $75M Hong Kong IPO debut

Dec. 24, 2025
By Tamra Sami
No Comments
Hanx Biopharmaceuticals (Wuhan) Co., Ltd. raised HK$586 million (US$75.37 million) in its IPO on the Hong Kong Securities Exchange (HKEX:3378) on Dec. 23 to advance its clinical stage immuno-oncology pipeline.
Read More
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