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BioWorld - Wednesday, March 4, 2026
Home » Topics » Drugs » Bispecific antibody

Bispecific antibody
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Cancer tumor in breast illustration

Systimmune’s iza-bren hits phase III breast cancer goals in China

March 3, 2026
By Marian (YoonJee) Chu
No Comments
In a boon for licensee Bristol Myers Squibb Co., Systimmune Inc.’s next-generation cancer drug, izalontamab brengitecan (iza-bren), hit both progression-free survival and overall survival endpoints in a phase III trial of Chinese patients with advanced triple-negative breast cancer.
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Cancer tumor in breast illustration

Systimmune’s iza-bren hits phase III breast cancer goals in China

Feb. 27, 2026
By Marian (YoonJee) Chu
No Comments
In a boon for licensee Bristol Myers Squibb Co., Systimmune Inc.’s next-generation cancer drug, izalontamab brengitecan (iza-bren), hit both progression-free survival and overall survival endpoints in a phase III trial of Chinese patients with advanced triple-negative breast cancer.
Read More
Illustration of macrophage releasing cytokines
Inflammatory

Ailux characterizes ALX-001 for IMIDs

Feb. 24, 2026
No Comments
Researchers from Shanghai Ailux Biotechnology Co. Ltd. have disclosed preclinical data regarding their humanized bispecific antibody ALX-001 targeting TL1A and IL-23 for the potential treatment of immune-mediated inflammatory diseases (IMIDs).
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Bispecific antibodies with heavy chain in green and pink, light chain in blue and yellow
Immuno-oncology

First-in-class LTβR x EDB bispecific antibody overcomes checkpoint resistance

Feb. 23, 2026
No Comments
Researchers from Agni Bio Inc. reported the preclinical profile of AGB-201, a bispecific antibody designed to simultaneously target EDB and LTβR, while minimizing unwanted immune activation.
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Park Tae-yong, vice president and cofounder, Galux
Newco news

AI meets antibody design: Galux draws $29M series B for drug R&D

Feb. 10, 2026
By Marian (YoonJee) Chu
No Comments
Galux closed a ₩42 billion (US$29 million) series B round Feb. 10, led by Yuanta Investment to bring AI-driven “rational design” to the protein drug development process, already heavily influenced by human engineering. 
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Park Tae-yong, vice president and cofounder, Galux
Drug design, drug delivery & technologies

AI meets antibody design: Galux draws $29M series B for drug R&D

Feb. 10, 2026
By Marian (YoonJee) Chu
No Comments
Galux closed a ₩42 billion (US$29 million) series B round Feb. 10, led by Yuanta Investment to bring AI-driven “rational design” to the protein drug development process, already heavily influenced by human engineering.
Read More
3D illustration of the cross-section of skin layers with atopic dermatitis
Dermatologic

Almirall files CTA for bispecific antibody for atopic dermatitis

Feb. 10, 2026
No Comments
Almirall SA has submitted a CTA filing for a bispecific antibody targeting IL-13 and OX-40L for the treatment of atopic dermatitis. The company expects to initiate a first-in-human phase I trial during the first half of this year.
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Park Tae-yong, vice president and cofounder, Galux
Newco news

AI meets antibody design: Galux draws $29M series B for drug R&D

Feb. 9, 2026
By Marian (YoonJee) Chu
No Comments
Galux closed a ₩42 billion (US$29 million) series B round Feb. 10, led by Yuanta Investment to bring AI-driven “rational design” to the protein drug development process, already heavily influenced by human engineering. 
Read More
Illustration of intestines with inflammation
Gastrointestinal

Sinorda Biomedicine and Wuxi Biologics collaborate on SND-006

Jan. 29, 2026
No Comments
Wuxi Biologics Co. Ltd. and Sinorda Biomedicine have established a strategic collaboration for the development and manufacturing of SND-006, a novel bispecific antibody, for the treatment of inflammatory bowel disease and other autoimmune diseases.
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Green and red bispecific antibodies

Boehringer nabs preclinical IBD bispecific in $1.2B Simcere pact

Jan. 28, 2026
By Marian (YoonJee) Chu
No Comments
Boehringer Ingelheim International GmbH signed a €1.058 billion (US$1.26 billion) deal with Simcere Pharmaceutical Group Ltd. to license select rights to SIM-0709, a preclinical TL1A/IL-23p19-directed bispecific antibody targeting inflammatory bowel disease (IBD).
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