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BioWorld - Tuesday, August 4, 2026
Home » Topics » Drugs » Oncolytic

Oncolytic
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Illustration of cancer on the esophagus

Japan backs Oncolys virus therapy for esophageal cancer

June 9, 2026
By Tamra Sami
No Comments
Japan has granted marketing approval to Oncolys Biopharma Inc.’s oncolytic adenovirus product, Telomelysin (suratadenoturev, OBP-301), for treating esophageal cancer in patients who are not eligible for curative resection or chemoradiotherapy. The approval marks the first oncolytic adenovirus product approved for esophageal cancer.
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3D illustration showing presence of tumor inside prostate gland

Advancell sets new radiopharma standard in prostate cancer

Nov. 11, 2025
By Tamra Sami
No Comments
Aussie radiopharma company Advancell Co. Ltd. unveiled promising early clinical data that could redefine how advanced prostate cancer is treated by targeted alpha therapies in the radiopharmaceutical space.
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3D illustration showing presence of tumor inside prostate gland

Advancell sets new radiopharma standard in prostate cancer

Nov. 7, 2025
By Tamra Sami
No Comments
Aussie radiopharma company Advancell Co. Ltd. unveiled promising early clinical data that could redefine how advanced prostate cancer is treated by targeted alpha therapies in the radiopharmaceutical space.
Read More
3D illustration showing presence of tumor inside prostate gland

Advancell sets new radiopharma standard in prostate cancer

Nov. 6, 2025
By Tamra Sami
No Comments
Aussie radiopharma company Advancell Co. Ltd. unveiled promising early clinical data that could redefine how advanced prostate cancer is treated by targeted alpha therapies in the radiopharmaceutical space.
Read More
Illustration of cancer in the pancreas

Theriva’s VCN-01 improves survival in phase IIb pancreatic cancer trial

May 7, 2025
By Jennifer Boggs
No Comments
Theriva Biologics Inc.’s stroma-targeting oncolytic virus approach yielded positive findings in metastatic pancreatic ductal adenocarcinoma, with the top-line readout of phase IIb data showing VCN-01 (zabilugene almadenorepvec) in combination with chemotherapy bested chemotherapy alone on primary and secondary endpoints, which included overall survival.
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Vial of Advancell's Alpha-212 isotope

Radiopharma Advancell raises $112M in series C for alpha therapies

Feb. 4, 2025
By Tamra Sami
Aussie radiopharma company Advancell Co. Ltd. closed an oversubscribed $112 million series C round that will accelerate clinical development of its pipeline of radionuclide therapies and allow it to expand its manufacturing capacity.
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Line graph arrow trending upward

Wick-ed good phase III prostate cancer data light up Candel

Dec. 11, 2024
By Randy Osborne
Candel Therapeutics Inc. followed this spring’s positive phase II data in pancreatic cancer with favorable results from a phase III study testing the same drug – viral immunotherapy CAN-2409 – in localized prostate cancer. Shares of Needham, Mass.-based Candel (NASDAQ:CADL) closed Dec. 11 at $7.75, up $3.14, or 68%.
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China’s NMPA accepts Ascentage NDA for Bcl-2 inhibitor lisaftoclax

Nov. 19, 2024
By Tamra Sami
China’s National Medical Products Administration (NMPA) has accepted Ascentage Pharma Group Corp. Ltd.’s NDA for its in-house-developed Bcl-2 selective inhibitor, lisaftoclax (APG-2575), which could be the first domestically approved Bcl-2 inhibitor in China and the second global approval.
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Conceptual image for brain cancer treatment

Oncolytic virus therapy may soon change glioma care: Bio Japan

Oct. 15, 2024
By Marian (YoonJee) Chu
Virus is associated with sickness, but oncolytic virus therapies, which harness viruses to attack and kill cancer cells, may soon change the standard of treatment for cancer, including those long deemed uncurable like malignant glioma.
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Conceptual image for brain cancer treatment

Oncolytic virus therapy may soon change glioma care: Bio Japan

Oct. 10, 2024
By Marian (YoonJee) Chu
Virus is associated with sickness, but oncolytic virus therapies, which harness viruses to attack and kill cancer cells, may soon change the standard of treatment for cancer, including those long deemed uncurable like malignant glioma.
Read More
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