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Home » Topics » Drugs » Vaccine

Vaccine
Vaccine RSS Feed RSS

Brain and DNA
Neurology/psychiatric

GA-VAX-01 shows promising results for C9orf72-associated ALS and FTD

July 10, 2024
Many patients with amyotrophic lateral sclerosis (ALS) or frontotemporal dementia (FTD) harbor the (G4C2)n pathogenic repeat expansion in the C9orf72 gene, which leads to aggregating dipeptide proteins, mainly poly-glycine-alanine (poly-GA).
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Hillevax plunges on phase IIb norovirus vaccine flop in infants

July 8, 2024
By Jennifer Boggs
Hillevax Inc. is turning its attention to preventing moderate or severe acute gastroenteritis events (AGEs) in adults with norovirus after the phase IIb NEST-IN1 trial testing virus-like particle-based vaccine HIL-214 in infants missed its primary and secondary endpoints, news that sent shares of the company (NASDAQ:HLVX) plummeting 88% to close July 8 at $1.64, a significant drop from the IPO price of $17 two years ago.
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Curevac enters ‘new chapter’ with $1.6B GSK deal, restructuring

July 3, 2024
By Nuala Moran
Curevac AG is casting off the deadweight of its pandemic push to translate its mRNA technology into a marketed COVID-19 vaccine, in a new €1.45 billion (US$1.6 billion) deal in which GSK plc will acquire full rights to infectious disease vaccines the two were co-developing.
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Jaeyong Ahn, CEO and president, SK Bioscience

SK Bioscience to acquire Klocke’s CDMO in cross-holding M&A

July 2, 2024
By Marian (YoonJee) Chu
South Korea’s SK Bioscience Co. Ltd. has entered a cross-shareholding acquisition deal with Germany’s Klocke Pharma-Service GmbH to acquire its contract development and manufacturing organization (CDMO), IDT Biologika Corp.
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Illustration of Shigella bacteria infecting the large intestine
Infection

L-DBF vaccine confers protection against shigellosis

June 28, 2024
Shigella flexneri is the leading cause of endemic diarrhea and dysentery in some countries with low-to-middle incomes. There is still a lack of a licensed vaccine against this pathogen.
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Jaeyong Ahn, CEO and president, SK Bioscience

SK Bioscience to acquire Klocke’s CDMO in cross-holding M&A

June 27, 2024
By Marian (YoonJee) Chu
South Korea’s SK Bioscience Co. Ltd. has entered a cross-shareholding acquisition deal with Germany’s Klocke Pharma-Service GmbH to acquire its contract development and manufacturing organization (CDMO), IDT Biologika Corp.
Read More
Transmission electron micrograph of HIV-1 virus particles
HIV/AIDS

HIV vaccine prototype induces gp41 broadly neutralizing antibodies

June 27, 2024
Researchers at The Scripps Research Institute and the IAVI Neutralizing Antibody Center are developing a novel experimental vaccine targeting the germline to stimulate precursor B cells and produce broadly neutralizing antibodies (bnAbs) against the membrane-proximal external region (MPER) of the gp41 protein found in the HIV-1 envelope.
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3D illustration of ovarian cancer cells
Immuno-oncology

Defence Therapeutics’ ARM-X cancer vaccine effective in ovarian cancer models

June 26, 2024
Defence Therapeutics Inc. has demonstrated that its second-generation ARM-X anticancer vaccine is therapeutically effective against pre-established ovarian cancer (ID8 model) when combined with an anti-PD-1 immune checkpoint inhibitor.
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Africa looks to do for itself with vaccine effort

June 20, 2024
By Mari Serebrov
The African Vaccine Manufacturing Accelerator is up and running, with more than $1 billion already pledged to the effort that’s aimed at supporting the sustainable growth of Africa's manufacturing base and contributing to the African Union's goal of producing 60% of the vaccines required by African countries by 2040.
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Merck’s pneumococcal vaccine, Capvaxive, wins US FDA approval

June 17, 2024
By Karen Carey
Becoming the first pneumococcal conjugate vaccine specifically designed for adults 18 and older, Merck & Co. Inc.’s 21-valent candidate, Capvaxive (V-116), gained U.S. FDA approval on its June 17 PDUFA date. The Rahway, N.J.-based company expects to take significant market share based on positive phase III findings from the Stride-3 trial. Analysts have estimated the product could reach $2 billion in annual global sales.
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