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BioWorld - Sunday, June 14, 2026
Home » Topics » Drugs » Vaccine

Vaccine
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Syringes in virus cell; Lilly, Curevo, Limmatech, Vaccine Company   logos

Lilly buys three vaccine makers; PCSK9 base editor shows promise

May 26, 2026
By Karen Carey
No Comments
As the most active biopharma acquirer of 2026, Eli Lilly and Co. offered to buy three vaccine companies for up to $3.8 billion combined, while it simultaneously released positive early clinical results of a gene editing medicine brought into the fold last year through its buyout of Verve Therapeutics Inc.
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3D illustration showing surface glycoprotein spikes hemagglutinin (purple) and neuraminidase (orange)
Infection

Dual adjuvant-HA stem nanoparticle vaccine generates protective immune response

May 26, 2026
No Comments
Although influenza virus infection can be particularly life-threatening among young infants, approved vaccines are lacking for infants under 6 months. Aiming to overcome the required annual updates to the influenza vaccine, recent efforts have focused on generating vaccines that promote broadly reactive antibodies (Abs) targeting conserved regions of viral proteins, such as the stem domain of hemagglutinin (HA).
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Microscopic view of the ebola virus

WHO declares Ebola outbreak a public health emergency of international concern

May 19, 2026
By Nuala Moran
No Comments
The threat posed by the Ebola outbreak in the Democratic Republic of Congo has intensified, with the confirmation that it is caused by the Bundibugyo species of the virus, for which there are no approved vaccines or antiviral therapies. At the same time, the high positivity rate, with eight laboratory confirmed cases out of 13 samples collected in various areas, and more reports of suspected cases and clusters of deaths, all point to a potentially much larger outbreak than currently is being detected and reported.
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Three syringes illustration

CDC vaccines panel to be ‘re-established’

May 19, 2026
By Mari Serebrov
No Comments
It’s back to the drawing board for the U.S. CDC’s Advisory Committee on Immunization Practices (ACIP). After a year of Health and Human Services Secretary Robert Kennedy gutting the panel and restocking it mostly with people who share his views on vaccines, the CDC published a notice in the May 19 Federal Register saying it’s withdrawing the amended ACIP charter renewal issued April 6 and is instead “re-establishing” the committee.
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Virus and vaccine illustration
Infection

Bundibugyo is harsh reminder of need for broad vaccine strategies

May 19, 2026
By Anette Breindl
No Comments
On Sunday, May 17th, 2026, the World Health Organization classified the ongoing Bundibugyo ebolavirus outbreak in the Democratic Republic of Congo (DRC) as a public health emergency of international concern (PHEIC). The rapid escalation to PHEIC is due to several factors. Given the high number of cases, the outbreak has likely been going undetected for some time, and may be a “much larger outbreak than what is currently being detected and reported, with significant local and regional risk of spread,” according to the WHO statement. The outbreak appears to already have crossed the border from the DRC into Uganda at least twice. And all this is happening with a virus for which there are no approved treatments or vaccines.
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Virus and vaccine illustration
Infection

Bundibugyo is harsh reminder of need for broad vaccine strategies

May 18, 2026
By Anette Breindl
No Comments
On Sunday, May 17th, 2026, the World Health Organization classified the ongoing Bundibugyo ebolavirus outbreak in the Democratic Republic of Congo (DRC) as a public health emergency of international concern (PHEIC). The rapid escalation to PHEIC is due to several factors. Given the high number of cases, the outbreak has likely been going undetected for some time, and may be a “much larger outbreak than what is currently being detected and reported, with significant local and regional risk of spread,” according to the WHO statement. The outbreak appears to already have crossed the border from the DRC into Uganda at least twice. And all this is happening with a virus for which there are no approved treatments or vaccines.
Read More
Microscopic view of the ebola virus

WHO declares Ebola outbreak a public health emergency of international concern

May 18, 2026
By Nuala Moran
No Comments
The threat posed by the Ebola outbreak in the Democratic Republic of Congo has intensified, with the confirmation that it is caused by the Bundibugyo species of the virus, for which there are no approved vaccines or antiviral therapies. At the same time, the high positivity rate, with eight laboratory confirmed cases out of 13 samples collected in various areas, and more reports of suspected cases and clusters of deaths, all point to a potentially much larger outbreak than currently is being detected and reported.
Read More
Ebola virus particle

Authorities work to quickly sequence Ebola species in latest outbreak

May 15, 2026
By Jennifer Boggs
No Comments
If the recent hantavirus outbreak wasn’t enough to keep public health officials busy, a new Ebola virus disease outbreak has been confirmed by authorities in the Democratic Republic of the Congo. While sequencing is ongoing to identify the Ebola species, experts have noted early results suggesting it appears to be different from the Zaire species that has caused previous outbreaks, including the deadliest outbreak in West Africa a decade ago, meaning existing vaccines and antibody treatments likely will not be effective.
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Hantavirus cells

APAC monitors hantavirus as Singapore isolates 2 from cruise ship

May 12, 2026
By Marian (YoonJee) Chu
No Comments
Singapore’s Communicable Diseases Agency on May 7 said that it isolated two residents for hantavirus testing after the individuals disembarked from an Atlantic cruise ship on May 2 and May 6, respectively. The measure comes in response to the cluster of cases from the cruise ship, MV Hondius, that has resulted in three deaths so far.
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3D illustration of enveloped HIV

Two-step HIV vaccine induces broadly neutralizing antibodies

May 12, 2026
By Mar de Miguel
No Comments
A designed chimeric virus induced broadly neutralizing antibodies against the macaque equivalent of HIV. The strategy works in two steps: first it uses an envelope protein with a mutation that reduces the glycan shield that makes it invisible to the immune system, and then it exposes the part of the protein most likely to generate these antibodies capable of blocking many variants of the virus. The macaques developed potent and diverse antibodies with this approach, which pave the way for the development of an HIV-1 vaccine.
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